ArticleTropical medicine & international health : TM & IH2026
Eco-Epidemiological Study of Seropositivity Against Rickettsia and Leptospira Agents in Rural Areas of Urabá, Colombia.
Article in Tropical medicine & international health : TM & IH, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Subclinical Leptospiral Infections and Antibody Waning During Pregnancy: A Population-Based Cohort Study from Rural Sri Lanka.The American journal of tropical medicine and hygiene · 2026Article
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Abstract
introductionRickettsioses and leptospirosis are infectious diseases often underdiagnosed due to limited knowledge about their epidemiology, pathophysiology, and clinical aspects.
objectivesTo characterize the seroprevalence and seroincidence of Rickettsia and Leptospira agents and determine their associated factors in rural areas of Urabá, Antioquia, Colombia.
methodsAnalysis of seropositivity of a prospective study exploring sociocultural and ecological aspects of Rickettsia and Leptospira infection. A multinomial mixed logistic regression model analysed factors linked to seroprevalent cases, with descriptive analyses of seroincident cases.
resultsConcomitant seroprevalence against Rickettsia and Leptospira was 9.38% (95% CI: 6.08%-13.37%). Associated factors included age (ORa = 1.02; 95% CI 1.007-1.03), male gender (ORa = 3.06; 95% CI: 1.75-5.37), fever history (ORa = 1.71; 95% CI: 1.06-2.77), presence of breeding pigs (ORa = 2.29; 95% CI 1.36-3.88), peridomicile yucca crops (ORa = 2.5; 95% CI 1.1-5.62), and deforestation practices (ORa = 1.74; 95% CI 1.06-2.87). Concomitant seroincidence was 1.09% (3/274) (95% CI: 0.29%-4.05%). All seroincident cases were female, median age 31.83 years (IQR: 8.69-56.99), with similar housing characteristics (soil floors, wooden walls, zinc roofs) and exposure to domestic and synanthropic animals.
conclusionsThere is evidence of concomitant seroprevalent and seroincident cases against both microorganisms in rural Urabá, Colombia. These findings can improve public health surveillance systems in preventing, detecting, and managing clinical cases caused by these pathogens.
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