Evidence map›Paper›PMID 42402351›Full record

ArticlePediatric obesity2026

Prenatal Bisphenol A Exposure and Sex-Differentiated Childhood BMI Over Time: A Longitudinal Korean Cohort Study.

Youn-Hee Lim, Yun-Chul Hong, Yun Jeong Lee, Choong Ho Shin, Dongwook Lee, Bung-Nyun Kim, Johanna Inhyang Kim, Young Ah Lee

Abstract read
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Article in Pediatric obesity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Youn-Hee LimSection of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Yun-Chul HongDepartment of Preventive Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
Yun Jeong LeeDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, Republic of Korea.
Choong Ho ShinDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, Republic of Korea.
Dongwook LeeDepartment of Preventive Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
Bung-Nyun KimDivision of Children and Adolescent Psychiatry, Department of Psychiatry, Seoul National University Hospital, Seoul, Republic of Korea.
Johanna Inhyang KimDepartment of Psychiatry, Hanyang University College of Medicine, Seoul, Republic of Korea.
Young Ah LeeDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0001-9179-1247

Funding

Ministry of Food and Drug Safety 15162MFDS046National Research Foundation of Korea 2018R1D1A1B07043446National Research Foundation of Korea 2018R1D1A1B07049806
6 · The paper itself

Abstract

backgroundPrenatal exposure to bisphenol A (BPA), an endocrine-disrupting chemical, may influence childhood obesity. Evidence on sex-specific effects remains inconsistent.

methodsWe analysed 528 mother-child pairs from a Korean birth cohort. Maternal urinary BPA concentrations were measured during mid-pregnancy. Children's BMI and BMI Z-score were assessed at ages 2, 4, 6, 8, and 10 years. Associations were estimated using linear and mixed-effects models, stratified by sex and adjusted for maternal and child covariates.

resultsThe mean maternal BPA concentration was 2.3 μg/g creatinine. BPA exposure was positively associated with BMI and BMI Z-score in boys but negatively associated in girls. At age 10, this divergence was most apparent. Mixed-effects models showed a 0.13 kg/m

conclusionsPrenatal BPA exposure exhibited sexually dimorphic associations with BMI from early childhood to age 10. These findings underscore the importance of considering sex-specific effects in environmental health research and support policies to reduce BPA exposure during pregnancy.

Indexed as

Benzhydryl CompoundsBody Mass IndexEndocrine DisruptorsPediatric ObesityPhenolsPrenatal Exposure Delayed EffectsAdultBisphenol A CompoundsChildChild, PreschoolFemaleHumansLongitudinal StudiesMalePregnancyRepublic of KoreaBenzhydryl Compoundsbisphenol ABisphenol A CompoundsEndocrine DisruptorsPhenolsbisphenol Abody mass indexprenatal effectssex‐specific effect

Identifiers

PMID42402351
PMCPMC13333248

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.