ArticleBone & joint research2026
Bone tracer uptake in SPECT/CT is a potential indicator for treatment decision-making in cystic osteochondral lesions of the talus.
Xiangyun Cheng, Bingyao Cai, Le Song, Tong Su, Hao Xu, Jirong Wang, XiaoLe Zhang, Yuelin Hu, Qinwei Guo, Chen Jiao and 1 more
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In one paragraphArticle in Bone & joint research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
11 authors.
Xiangyun ChengDepartment of Sports Medicine, Peking University Third Hospital; Institute of Sports Medicine of Peking University; Beijing Key Laboratory of Sports Injuries; Engineering Research Center of Sports Trauma Treatment Technology and Devices, Ministry of Education, Beijing, China.ORCID 0000-0003-0146-0757 Bingyao CaiDepartment of Sports Medicine, Peking University Third Hospital; Institute of Sports Medicine of Peking University; Beijing Key Laboratory of Sports Injuries; Engineering Research Center of Sports Trauma Treatment Technology and Devices, Ministry of Education, Beijing, China.ORCID 0009-0004-6374-3650 Le SongDepartment of Nuclear Medicine, Peking University Third Hospital, Beijing, China.
Tong SuDepartment of Sports Medicine, Peking University Third Hospital; Institute of Sports Medicine of Peking University; Beijing Key Laboratory of Sports Injuries; Engineering Research Center of Sports Trauma Treatment Technology and Devices, Ministry of Education, Beijing, China.
Hao XuDepartment of Sports Medicine, Peking University Third Hospital; Institute of Sports Medicine of Peking University; Beijing Key Laboratory of Sports Injuries; Engineering Research Center of Sports Trauma Treatment Technology and Devices, Ministry of Education, Beijing, China.
Jirong WangDepartment of Orthopedics, The 951st Hospital of the People's Liberation Army, Korla, China.
XiaoLe ZhangDepartment of Sports Medicine, Peking University Third Hospital; Institute of Sports Medicine of Peking University; Beijing Key Laboratory of Sports Injuries; Engineering Research Center of Sports Trauma Treatment Technology and Devices, Ministry of Education, Beijing, China.
Yuelin HuDepartment of Sports Medicine, Peking University Third Hospital; Institute of Sports Medicine of Peking University; Beijing Key Laboratory of Sports Injuries; Engineering Research Center of Sports Trauma Treatment Technology and Devices, Ministry of Education, Beijing, China.ORCID 0000-0002-3864-5942 Qinwei GuoDepartment of Sports Medicine, Peking University Third Hospital; Institute of Sports Medicine of Peking University; Beijing Key Laboratory of Sports Injuries; Engineering Research Center of Sports Trauma Treatment Technology and Devices, Ministry of Education, Beijing, China.ORCID 0000-0003-3600-9544 Chen JiaoDepartment of Sports Medicine, Peking University Third Hospital; Institute of Sports Medicine of Peking University; Beijing Key Laboratory of Sports Injuries; Engineering Research Center of Sports Trauma Treatment Technology and Devices, Ministry of Education, Beijing, China.ORCID 0000-0001-8611-871X Dong JiangDepartment of Sports Medicine, Peking University Third Hospital; Institute of Sports Medicine of Peking University; Beijing Key Laboratory of Sports Injuries; Engineering Research Center of Sports Trauma Treatment Technology and Devices, Ministry of Education, Beijing, China.ORCID 0000-0003-4380-7683 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
Aims: Cystic osteochondral lesions of the talus (OLTs) demonstrate metabolic dysregulation that predisposes to osteonecrosis, for which timely invasive intervention is crucial. This study aimed to investigate the predictive value of bone tracer uptake (BTU) of single-photon emission CT/CT (SPECT/CT) for conservative treatment outcomes, and promote a novel indicator for decision-making of the treatment of cystic OLTs. Methods: Patients with cystic OLTs who underwent SPECT/CT scanning from January 2020 to August 2024 received three-month conservative treatments. Maximum standardized uptake value (SUV Results: The Failure group had significantly higher mean SUV Conclusion: This study demonstrates that SPECT/CT-derived BTU is a potential indicator for treatment decision-making in cystic OLTs. Elevated BTU showed a statistically significant association with poor response to nonoperative care in this cohort. The critical threshold of SUV
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PMID42402336
PMCPMC13333215
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