Evidence map›Paper›PMID 42401945›Full record

ArticleBMC nutrition2026

Nutritional status in pediatric celiac disease: evaluation at diagnosis and during follow-up.

Seyhan Yılmaz, Sebahat İmamoğlu Çam

Abstract read
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Article in BMC nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Seyhan YılmazDivision of Pediatric Infectious Diseases, Department of Pediatrics, Marmara University School of Medicine, Istanbul, Türkiye.ORCID http://orcid.org/0000-0001-6873-0745
Sebahat İmamoğlu ÇamDivision of Pediatric Gastroenterology, Department of Pediatrics, School of Medicine, Istanbul Medeniyet University, Istanbul, Türkiye. imamoglus@yahoo.com.ORCID http://orcid.org/0000-0001-7394-3569

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCeliac disease (CD) is a lifelong immune-mediated condition precipitated by gluten ingestion in genetically predisposed individuals, resulting in intestinal mucosal damage, impaired growth, micronutrient deficiencies, among other gastrointestinal and extraintestinal symptoms. A gluten-free diet (GFD) contributes to the healing of the mucosa and improves nutrient absorption, although recovery patterns may vary.

aimThe present study aimed to determine changes in anthropometric parameters and micronutrient levels at diagnosis and at six and twelve months following the start of a GFD, and to investigate any associations between these changes and tissue transglutaminase IgA (tTG-IgA) status, the severity of mucosal damage, or clinical characteristics.

methodsThis retrospective investigation involved an assessment of pediatric individuals diagnosed with CD using anthropometric and micronutrient data collected at the point of diagnosis and at subsequent 6- and 12-month intervals following GFD. Dietary adherence was evaluated retrospectively using physician and dietitian follow-up notes, clinical assessment, and serial tTG-IgA measurements.

resultsAmong 103 children (64% female), 56% had no comorbidities, and type 1 diabetes was the most common (15%). Height, weight, body mass index, and most micronutrient levels improved during follow-up period. Vitamin D deficiency remained present in 27% of patients at 12 months and overweight prevalence increased from 7.8% to 18.4% during follow-up. Individuals presenting with comorbid CD+type 1 diabetes demonstrated higher SDS for weight and height, and elevated hemoglobin concentrations. The incidence of seronegativity was 55% at six months and 73% at twelve months.

conclusionWithin a year, GFD enhances growth and resolves the majority of micronutrient deficiencies, however; ongoing nutritional monitoring is crucial due to persistent vitamin D deficiency and an increasing risk of overweight.

Indexed as

Celiac diseaseGluten-free dietGrowth parametersMicronutrient status

Identifiers

PMID42401945
PMCPMC13613579

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