Evidence map›Paper›PMID 42401878›Full record

ArticleBMC oral health2026

3D-driven alveolar ridge augmentation based on reverse planning: a retrospective case series study.

Fanni Bolya-Orosz, Balint Molnar, Željka Perić Kačarević, Peter Windisch, Daniel Palkovics

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Article in BMC oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Fanni Bolya-OroszDepartment of Periodontology, Semmelweis University, Szentkirályi utca 47, Budapest, 1088, Hungary.
Balint MolnarDepartment of Periodontology, Semmelweis University, Szentkirályi utca 47, Budapest, 1088, Hungary.
Željka Perić KačarevićBotiss medical AG Ullsteinstraße 108, Ullsteinstraße 108, Berlin, 12109, Germany.
Peter Windisch *Department of Periodontology, Semmelweis University, Szentkirályi utca 47, Budapest, 1088, Hungary.
Daniel Palkovics *Department of Periodontology, Semmelweis University, Szentkirályi utca 47, Budapest, 1088, Hungary. palkovics.daniel@semmelweis.hu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundReconstruction of advanced vertical and combined alveolar ridge defects still remains a challenge in implant dentistry. Digital technologies and virtual planning may potentially improve the predictability of guided bone regeneration (GBR). This study aimed to evaluate a fully digital, reverse-planning workflow for vertical ridge augmentation using membrane-cutting guides.

methodsThis retrospective case series included 15 surgical sites presenting with vertical or combined alveolar ridge defects. A digital workflow integrating cone-beam computed tomography (CBCT), intraoral scanning, and virtual prosthetic planning was used to simulate ideal implant positions and corresponding hard tissue augmentation. Membrane-cutting guides were designed and fabricated using additive manufacturing to shape dense polytetrafluoroethylene membranes. Vertical GBR was performed using a split-thickness flap design and a tent-pole approach. Linear and volumetric hard tissue changes were assessed by comparing baseline and 9-month postoperative CBCT scans.

resultsSignificant vertical bone gain was observed at all measurement points (p = 0.007), with mean increases from 15.70 mm ± 4.34 mm to 19.96 mm ± 3.83 mm at the central site. The mean volumetric hard tissue gain was 755.33 mm

conclusionsThe proposed 3D-driven reverse-planning workflow enabled predictable vertical ridge augmentation with high agreement between planned and achieved outcomes. This approach represents a feasible and accessible alternative to fully customized systems; however, further prospective controlled studies are required to validate these findings.

Indexed as

Alveolar Ridge AugmentationImaging, Three-DimensionalCone-Beam Computed TomographyDental Implantation, EndosseousFemaleGuided Tissue Regeneration, PeriodontalHumansRetrospective StudiesCBCTDense PTFE membraneGuided bone regenerationGuided surgeryReverse engineeringVirtual planning

Identifiers

PMID42401878
PMCPMC13613832

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.