ArticleCancer causes & control : CCC2026
Exercise trajectories and current exercise and risk of breast cancer: a cohort study of 325,953 women who participated in BreastScreen Norway.
Article in Cancer causes & control : CCC, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of the study was to elucidate life-course and current exercise levels among women aged 50-69 who participated in BreastScreen Norway during the period from 2006 to 2015, and to estimate the risk of breast cancer based on exercise trajectory classes and current exercise level.
methodsSelf-reported data from 325,953 women were utilized for descriptive and exploratory analyses. Retrospective information about exercise levels at ages 15-19, 20-29, 30-39, and 40-49 was used to establish exercise trajectory classes, while reported exercise at ages 50-69 was considered as current activity. Hazard Ratios (HR) with 95% confidence intervals (CIs) were estimated using Cox proportional hazards models adjusting for age, educational level and body mass index (BMI).
resultsAdjusted HR of breast cancer was 0.92 (95% CI: 0.87-0.98) for women in the stable high class and 0.94 (95% CI: 0.89-0.99) for those in the increasing trajectory class compared to the stable low class. The HRs was 0.89 (95% CI: 0.82-0.97) for 4.5 h current exercise per week and 0.72 (95% CI: 0.62-0.84) for ≥ 6 h, compared to those reporting no current exercise. Statistically significant results were observed for asymptomatic (screen-detected) and symptomatic cancers. Stratification by BMI and smoking status did not reveal substantial differences in the risk estimates.
conclusionEngaging in high-level exercise throughout one's lifetime significantly reduces the risk of breast cancer. This study highlights the importance of maintaining or increasing physical activity levels throughout life to mitigate breast cancer risk.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.