ArticleJACC. Case reports2026
Secondary Cardiac Lymphoma Presenting as Effusive-Constrictive Pericarditis.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 authors.
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Abstract
backgroundDiffuse large B-cell lymphoma (DLBCL) may present as effusive constrictive pericarditis. CASE SUMMARY: A 40-year-old woman with relapsed high-grade DLBCL presented with worsening dyspnea and acute decompensated heart failure. Two weeks prior, she underwent a pericardial window with preserved left ventricular ejection fraction of 50%. On admission, transthoracic echocardiography revealed nodular pericardial thickening consistent with metastatic disease and a new reduction in left ventricular ejection fraction to 39%. Doppler imaging revealed expiratory diastolic hepatic vein flow reversal, ventricular interdependence with septal bounce, and annulus reversus with a medial mitral annular e' velocity preserved at 9 cm/s and a reduced lateral e' velocity of 6 cm/s. These findings were diagnostic of effusive-constrictive pericarditis following recent pericardial drainage. DISCUSSION: This case highlights secondary cardiac lymphoma as a rare cause of effusive-constrictive pericarditis and underscores the diagnostic importance of echocardiography. TAKE-HOME MESSAGE: DLBCL-related pericardial involvement carries a poor prognosis with limited therapeutic options.
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