ArticlePediatric pulmonology2026
Home Non-Invasive Ventilation as an Alternative to Tracheostomy in Infants With Moderate-to-Severe Bronchopulmonary Dysplasia: A Retrospective Cohort Study.
Article in Pediatric pulmonology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
BACKGROUND AND
objectiveImproved survival among extremely preterm infants has increased the prevalence of bronchopulmonary dysplasia (BPD) requiring respiratory support after neonatal intensive care unit (NICU) discharge. This study aimed to evaluate temporal trends in home respiratory support practices and compare clinical outcomes between infants with BPD discharged on supplemental oxygen, non-invasive positive airway pressure (NI-PAP), and tracheostomy ventilation (TV). We hypothesized that home NI-PAP is a feasible alternative to TV in appropriately selected infants, with comparable growth and neurodevelopmental outcomes and lower healthcare utilization.
methodsRetrospective cohort study of infants born at <32 weeks' gestation and discharged from a Level IV or III NICU in British Columbia between 2013 and 2022 on supplemental oxygen, NI-PAP, or TV for BPD management. Patient characteristics, healthcare utilization, and duration of support were described. Longitudinal growth and neurodevelopmental outcomes were compared using adjusted linear mixed-effects models.
resultsAmong 102 infants, 52% received supplemental oxygen, 39% NI-PAP, and 9% TV. NI-PAP use increased over time, while tracheostomy use declined. Infants on NI-PAP were discharged earlier, were younger at respiratory support discontinuation, and had fewer hospital readmissions than those receiving TV. Infants requiring TV had lower neurodevelopmental scores. Growth trajectories were similar.
conclusionsIn this cohort of infants with BPD requiring home respiratory support, NI-PAP use increased over time and was associated with shorter hospitalization and lower healthcare utilization compared with TV. Differences in outcomes likely reflect differences in disease severity and clinical complexity. NI-PAP may represent an appropriate management strategy for selected infants with moderate-to-severe BPD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.