Evidence map›Paper›PMID 42400496›Full record

ArticlemSphere2026

Systems analysis reveals alternate metabolic states adopted by

Jonathan Padilla-Gomez, Rachel McGinn, Victoria De Andrade, Yisha Liang, Kendra Libby, Heyuan Michael Ni, Alison E Ringel, Charles L Evavold, Bryan D Bryson

Abstract read
In one paragraph

Article in mSphere, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Jonathan Padilla-GomezDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.ORCID 0009-0002-6748-361X
Rachel McGinnDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.ORCID 0000-0002-2340-3318
Victoria De AndradeRagon Institute of Mass General, MIT and Harvard, Cambridge, Massachusetts, USA.
Yisha LiangRagon Institute of Mass General, MIT and Harvard, Cambridge, Massachusetts, USA.
Kendra LibbyRagon Institute of Mass General, MIT and Harvard, Cambridge, Massachusetts, USA.
Heyuan Michael NiDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.ORCID 0000-0003-0881-7245
Alison E RingelRagon Institute of Mass General, MIT and Harvard, Cambridge, Massachusetts, USA.
Charles L EvavoldRagon Institute of Mass General, MIT and Harvard, Cambridge, Massachusetts, USA.
Bryan D BrysonDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.ORCID 0000-0003-1716-6712

Funding

The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI ARTHUR Y KIM · 2004 to 2026
$94.4M
Dynamics of the cellular and molecular architecture of human pulmonary TB granulomasR01AI166313 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ROBERT L MODLIN · 2022 to 2026
$3.2M
Type I IFN-dependent and independent contributions to the outcomes of early innate immune cell interactions during HIV/TB co-infectionR01AI184666 · NIAID · WASHINGTON UNIVERSITY · PI Bryan David Bryson, Joshua T. Mattila · 2024 to 2026
$2.6M
High-dimensional characterization of phagosome composition, control and phagocytic receptor redundancyR35GM142900 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI BRYSON, BRYAN DAVID · 2021 to 2025
$2.1M
NIAID NIH HHS P30 AI060354NIAID NIH HHS R01 AI166313NIAID NIH HHS R01 AI184666NIGMS NIH HHS R35 GM142900NIH HHS R01AI166313, R35GM142900, R01AI184666
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Host-Pathogen InteractionsMacrophagesMycobacterium tuberculosisAnimalsGene Expression ProfilingHumansLipid MetabolismMiceSpecies SpecificityTuberculosisinnate immunitymacrophagesMycobacterium tuberculosis

Identifiers

PMID42400496
PMCPMC13410760

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.