Evidence map›Paper›PMID 42400442›Full record

ArticleThe Laryngoscope2026

Vocal Fold Opening Position Impacts Bowing Measures in Age-Related Vocal Atrophy.

Carson S Miller, Byron S Kim, Mahdi Al-Ghezi, Zaroug A Jaleel, Lisa A Zughni, Neel K Bhatt

Abstract read
In one paragraph

Article in The Laryngoscope, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carson S MillerDivision of Laryngology, Department of Otolaryngology-Head and Neck Surgery, University of Washington School of Medicine, Seattle, Washington, USA.ORCID https://orcid.org/0000-0002-9317-1815
Byron S KimDivision of Laryngology, Department of Otolaryngology-Head and Neck Surgery, University of Washington School of Medicine, Seattle, Washington, USA.ORCID https://orcid.org/0009-0004-1453-1897
Mahdi Al-GheziDivision of Laryngology, Department of Otolaryngology-Head and Neck Surgery, University of Washington School of Medicine, Seattle, Washington, USA.
Zaroug A JaleelDivision of Laryngology, Department of Otolaryngology-Head and Neck Surgery, University of Washington School of Medicine, Seattle, Washington, USA.
Lisa A ZughniDivision of Laryngology, Department of Otolaryngology-Head and Neck Surgery, University of Washington School of Medicine, Seattle, Washington, USA.
Neel K BhattDivision of Laryngology, Department of Otolaryngology-Head and Neck Surgery, University of Washington School of Medicine, Seattle, Washington, USA.ORCID https://orcid.org/0000-0002-8933-5477

Funding

Neuromuscular changes in the aging larynxK08AG090629 · NIA · UNIVERSITY OF WASHINGTON · PI Neel Kishor Bhatt · 2025 to 2026
$324k
NIA NIH HHS K08 AG090629NIH HHS 1K08AG090629-01A1
6 · The paper itself

Abstract

objectivesAge-related vocal atrophy (ARVA) impacts voice and quality of life. In ARVA, vocal folds appear thin and bowed. Bowing Index (BI) is used to quantify vocal fold bowing. However, it remains unclear how abduction and adduction of the vocal folds influence BI. The purpose of this study was to assess the relationship of BI to vocal fold task and angle.

methodsPatients with ARVA were included (n = 22). Flexible video laryngostroboscopy was collected during an alternating voice-sniff task, during which vocal folds transition from adducted (closed) to fully abducted (open) positions. BI was measured at each non-phonatory frame. Two clinical raters then rated each subject by severity, and their ratings were compared to BI.

resultsMean BI was higher during vocal fold abduction than adduction (8.15 ± 3.29, 6.34 ± 2.21, respectively, mean difference 1.81, 95% CI: 1.25-2.38, p < 0.0001). Mean BI was higher when vocal folds were between 40% and 60% of maximal abduction compared to 80%-100% (mean difference 2.61, 95% CI: 1.26-3.96, p < 0.0001). Mean BI increased with clinical severity (7.30 ± 1.85 mild; 8.90 ± 2.52 moderate), with a BI of 14.62 in the single severe case.

conclusionVocal fold bowing is influenced by the degree of opening and the adduction versus abduction tasks in patients with ARVA. Bowing was greater during the abducting task than during the adducting task, with the most pronounced bowing observed at a semi-abducted position. Future studies are warranted to further characterize these findings and to support standardization of BI measurement. LEVEL OF EVIDENCE: N/A.

Indexed as

AgingVocal CordsAdultAgedAtrophyFemaleHumansLaryngoscopyMaleMiddle AgedStroboscopyVideo Recordingage‐related vocal fold atrophyendoscopypresbylarynxvocal fold bowing

Identifiers

PMID42400442
PMCPMC13367414

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.