Evidence map›Paper›PMID 42400411›Full record

ArticleJournal of public health management and practice : JPHMP

Implementation Evaluation of a Multicomponent Intervention to Address the Infectious Disease and Overdose Syndemic Among People Who Use Drugs in Rural Settings.

Mai T Pho, Beth Prusaczyk, Ellen Almirol, Scott Fletcher, William Nicholson, Jerel M Ezell, Suzan M Walters, Erin Augustine, Rebecca R Bolinski, John Bresett and 14 more

Abstract read
In one paragraph

Article in Journal of public health management and practice : JPHMP. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Mai T PhoAuthor Affiliations: University of Chicago Medicine, Chicago, IL (Pho, Almirol, Ezell, Augustine, Schneider, Lee, Tilmon, and Johnson); Washington University School of Medicine, St. Louis, MO (Prusaczyk); Southern Illinois Resource and Advocacy Center, Murphysboro, IL (Fletcher, Nicholson, and Miller); New York University Grossman School of Medicine, New York, NY (Walters, and Friedman); Southern Illinois University, Carbondale, IL (Bolinski); Southern Illinois University at Edwardsville, Edwardsville, IL (Bresett); Southern Illinois University, School of Medicine, Center for Rural Health and Social Service Development, Carbondale, IL (Vanham); University of Illinois Urbana-Champaign, Urbana, IL (Kolak); University of Illinois at Chicago, Chicago, IL (Ouellet); University of Wisconsin Madison, Madison, WI (Salisbury-Afshar); Southern Illinois University School of Medicine, Springfield, IL (Sattovia, Han); and Clemson University, Clemson, SC (Jenkins).ORCID 0009-0005-4030-9226
Scott Fletcher
William NicholsonORCID 0009-0003-2295-2141
Jerel M Ezell
Erin Augustine
Rebecca R Bolinski
Kyle Miller
Brent Vanham
John A Schneider
Marynia A Kolak
Samuel R FriedmanORCID 0000-0003-2083-1226
Lawrence J OuelletORCID 0000-0003-0876-6556
Elizabeth Salisbury-AfsharORCID 0000-0003-4096-6822
Stacy Sattovia

Funding

Ending transmission of HIV, HCV, and STDs and overdose in rural communities of people who inject drugs (ETHIC)UH3DA044829 · NIDA · UNIVERSITY OF CHICAGO · PI JENKINS, WILEY, PHO, MAI TUYET · 2019 to 2022
$5.2M
Ending transmission of HIV, HCV, and STDs and overdose in rural communities of people who inject drugs (ETHIC)UG3DA044829 · NIDA · UNIVERSITY OF CHICAGO · PI JENKINS, WILEY, PHO, MAI TUYET · 2017 to 2018
$1.1M
NIDA NIH HHS DA044829NIDA NIH HHS UG3 DA044829NIDA NIH HHS UH3 DA044829
6 · The paper itself

Abstract

objectiveTo evaluate the effectiveness and implementation of a multicomponent intervention to address the burden of drug use-related infectious diseases and overdose in rural settings.

designSingle-arm hybrid implementation-effectiveness design.

settingRural area comprising the Illinois counties of the Delta Regional Authority.

participantsPeople who use opioids and/or stimulants nonmedically.

interventionExpansion of community-based harm reduction services, capacity-building for opioid use disorder and hepatitis C treatment.

main outcome measuresHarm reduction service expansion intervention Reach, Effectiveness (injection equipment sharing), Adoption and Cost (per participant and budget impact analysis).

resultsThree hundred six people who use drugs were enrolled. Of the 207 of who were not previously engaged in harm reduction services, 121 (59%) accepted referral and were retained in services at 6 months past study enrollment (intervention reach). In regards to intervention efficacy, among these individuals, 41 (35%) completed follow-up surveys; compared with their baseline self-report, there was a significant increase in obtaining sterile equipment from the harm reduction organization (43.9% vs. 68.3%, P = 0.03) and decrease in sharing injection equipment (46.3%-19.5%, P = .02). The harm reduction organization experienced an increase of approximately 100-550 program participants and an increase in service delivery area coverage from 1258 to 5509 square miles after intervention implementation (adoption). Cost per participant served by the harm reduction organization was $1486 per year, with annual budget impact to the program of $817 295. In regards to treatment capacity building, a total of 80 providers in the study area completed training in opioid use and/or hepatitis C management.

conclusionThe pragmatic evaluation of harm reduction service expansion supported by a suite of implementation strategies serves to inform the practical considerations and decision-making by community-based organizations seeking to increase services in rural areas heavily affected by substance use, overdose, and related infectious diseases.

Indexed as

Communicable DiseasesDrug OverdoseSubstance-Related DisordersAdultFemaleHarm ReductionHumansIllinoisProgram EvaluationRural Populationharm reductionimplementation researchrural substance use

Identifiers

PMID42400411
PMCPMC13378761

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.