Evidence map›Paper›PMID 42400181›Full record

SynthesisBioMed research international2026

Clinical Efficacy of Chinese Medicine in Treating Adult Henoch-Schönlein Purpura: A Meta-Analysis.

Otgongerel Nergui, Jin Huan Wang, He Dan Di, Ding Ding Li, Yang Yang Li, Xianghui Wan, Wei Yi, Wang Bin, Saruultuya Nergui, Ganchimeg Dondov and 3 more

Abstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BioMed research international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Otgongerel NerguiDepartment of Hematology, First Affiliated hospital, Heilongjiang University of Chinese Medicine, Harbin, China, hljucm.edu.cn.
Jin Huan WangDepartment of Hematology, First Affiliated hospital, Heilongjiang University of Chinese Medicine, Harbin, China, hljucm.edu.cn.
He Dan DiDepartment of Internal Medicine, Heilongjiang University of Chinese Medicine, Harbin, China, hljucm.edu.cn.ORCID https://orcid.org/0000-0001-8464-0168
Ding Ding LiDepartment of Internal Medicine, Heilongjiang University of Chinese Medicine, Harbin, China, hljucm.edu.cn.
Yang Yang LiDepartment of Internal Medicine, Heilongjiang University of Chinese Medicine, Harbin, China, hljucm.edu.cn.
Xianghui WanDepartment of Internal Medicine, Heilongjiang University of Chinese Medicine, Harbin, China, hljucm.edu.cn.
Wei YiDepartment of Internal Medicine, Heilongjiang University of Chinese Medicine, Harbin, China, hljucm.edu.cn.
Wang BinDepartment of Internal Medicine, Heilongjiang University of Chinese Medicine, Harbin, China, hljucm.edu.cn.
Saruultuya NerguiDepartment of Internal Medicine, Heilongjiang University of Chinese Medicine, Harbin, China, hljucm.edu.cn.
Ganchimeg DondovDepartment of Internal Medicine, Institute of Medical Sciences, Ulaanbaatar, Mongolia.ORCID https://orcid.org/0000-0001-6314-6996
Tegshjargal BadamjavDepartment of Internal Medicine, Institute of Medical Sciences, Ulaanbaatar, Mongolia.ORCID https://orcid.org/0000-0001-9982-949X
Tulgaa LonjidDepartment of Internal Medicine, Institute of Medical Sciences, Ulaanbaatar, Mongolia.ORCID https://orcid.org/0000-0002-2565-0347
Batbold BatsaikhanDepartment of Internal Medicine, Institute of Medical Sciences, Ulaanbaatar, Mongolia.ORCID https://orcid.org/0000-0003-3109-2166

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis meta-analysis evaluates the efficacy of traditional Chinese medicine, alone or in combination with Western medicine, for the treatment of adult Henoch-Schönlein purpura.

methodsWe searched clinical randomized controlled trials on the treatment of adult Henoch-Schönlein purpura with traditional Chinese medicine from the Chinese Journal Literature Database (CNKI), Wanfang Database, Embase, PubMed, Cochrane, Scopus, the Journal of Pharmacopuncture, and the National Library of China. After removing duplicate literature and reviewing titles, we selected the final studies based on our inclusion and exclusion criteria. These studies were assessed for bias using the Cochrane risk of bias assessment tool, and statistical analysis was performed using Review Manager 5.3.0 software. The PRISMA guidelines were followed when conducting the meta-analysis.

resultsEighteen studies were included, with a combined sample size of 1632 cases, including 811 in the experimental group and 821 in the control group. The results indicated that traditional Chinese medicine, whether used alone or in combination with Western medicine, was more effective than Western medicine alone in terms of overall effectiveness and improvement in skin purpura, digestive tract, and joint symptoms. We found that the total clinical effective rate of patients in the experimental group was higher than that of the control group (OR = 6.04, 95% CI [4.01, 9.10], p < 0.001). Meta-analysis indicates that the difference between the control and experimental groups in improving skin purpura symptoms is statistically significant (SMD = -1.09, 95% CI [-1.22, -0.96], p < 0.001). We found that a more significant improvement occurred in the experimental group than in the control group (SMD = -0.95, 95% CI [-1.08, -0.82], p < 0.001). People in the experimental group showed a greater decrease in joint symptoms than those in the control group (SMD = -0.95, 95% CI [-1.08, -0.82], p < 0.001).

conclusionTraditional Chinese medicine, either alone or combined with Western medicine, is more effective than Western medicine alone in treating Henoch-Schönlein purpura. It also shows superior efficacy in improving skin purpura, digestive tract, and joint symptoms.

Indexed as

Drugs, Chinese HerbalIgA VasculitisMedicine, Chinese TraditionalAdultHumansRandomized Controlled Trials as TopicTreatment OutcomeDrugs, Chinese HerbalChinese and Western medicineHenoch–Schönlein purpuratraditional Chinese medicine

Identifiers

PMID42400181
PMCPMC13332133

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.