Evidence map›Paper›PMID 42399804›Full record

ArticleBMC geriatrics2026

Community-based chest X-ray screening versus symptom-based case presentation in the elderly: evidence from three consecutive years of data.

Kui Liu, Ziyang Fang, Bin Chen, Yaling Feng, Zhicheng Yu, Yi Yu, Tao Jiang, Jianmin Jiang, Hui Zhang

Abstract readComparative Study
In one paragraph

Article in BMC geriatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kui Liu *National Center for Tuberculosis Control and Prevention, Chinese Center for Disease Control and Prevention & Chinese Academy of Preventive Medicine, Beijing, China.
Ziyang Fang *Ningbo University, Ningbo, China.
Bin ChenDepartment of Tuberculosis Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China.
Yaling FengLanxi City Center for Disease Control and Prevention, Jinhua, China.
Zhicheng YuLanxi City Center for Disease Control and Prevention, Jinhua, China.
Yi YuHangzhou Xiaoshan Hospital of Traditional Chinese Medicine, Hangzhou, China.
Tao JiangDepartment of Tuberculosis Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China.
Jianmin JiangDepartment of Tuberculosis Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China. jmjiang@cdc.zj.cn.
Hui ZhangNational Center for Tuberculosis Control and Prevention, Chinese Center for Disease Control and Prevention & Chinese Academy of Preventive Medicine, Beijing, China. zhanghui@chinacdc.cn.

Funding

Disease Prevention and Control Innovation Team of Zhejiang Province 2026JKC-05Pioneer and Leading Goose R&D Program of Zhejiang 2025C01134the National Science and Technology Major Project 2025ZD01901004Zhejiang Provincial Medical and Health Project 2025KY774Zhejiang Science and Technology Plan for Disease Prevention and Control 2026JKY294
6 · The paper itself

Abstract

backgroundCommunity-based chest X-ray (CXR) screening has been widely performed to improve tuberculosis identification in elderly populations, but comparative evidence against mode of symptom-driven case finding remains scarce.

methodsWe conducted three annual rounds of mass CXR screening among individuals aged over 60 years in Lanxi City, China, from 2021 to 2023. Tuberculosis cases identified through CXR screening were compared with concurrent, symptom-driven case presentations via routine surveillance. Restricted cubic spline and multivariable logistic regression analyses were used to examine factors associated with distinct detection pathways.

resultsAt the individual level, a total of 831 tuberculosis cases were identified through two modes. CXR mass screening detected more patients with less typical symptoms, while symptom-driven detection was more effective in females (aOR = 0.59, 95% CI 0.39-0.88), bacteriologically confirmed cases (aOR = 0.42, 95% CI 0.27-0.63), and those aged greater than 80 (aOR = 0.50, 95% CI 0.30-0.82). Age showed a nonlinear association with mass screening yield, with peak effectiveness between 60 and 66 years while no significance was found for BMI. In population-level analysis, CXR mass screening outperformed symptom-driven detection for case identification in the first round but declined and reversed by the third round. Subgroup analyses revealed potential benefits among individuals with diabetes or prior tuberculosis history, particularly within two years post-diagnosis or treatment.

conclusionsCommunity-based CXR screening could effectively detect incremental tuberculosis cases with atypical or mild symptoms. The young-old would benefit from mass CXR screening, while more accessible services were needed for the very elderly. Elderly individuals with diabetes or prior tuberculosis history should be prioritized, with intensified monitoring within two years after diagnosis or treatment completion.

Indexed as

Mass Chest X-RayMass ScreeningRadiography, ThoracicTuberculosis, PulmonaryAgedAged, 80 and overChinaFemaleHumansMaleMiddle AgedBMIChest radiographyDiabetesMass screeningTuberculosis

Identifiers

PMID42399804
PMCPMC13613845

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.