Evidence map›Paper›PMID 42399592›Full record

ArticleNeuroscience bulletin2026

Hierarchical Studies in TRAP2 Mice Demonstrate that Neuronal Activation and Mitochondrial Networks Integration Constitute the Key Mechanism Underlying Painful Syncope.

Xueyin Pu, Yulu Xia, Ziwei Ni, Changlei Zhu, Kunlong Zhang, Bozhi Liu, Rui Lin, Jingxuan Zhu, Hui Liu, Shujiao Li and 8 more

Abstract read
PubMed Publisher
In one paragraph

Article in Neuroscience bulletin, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Xueyin Pu *School of Basic Medical Sciences, Fourth Military Medical University, Laboratory of Mitochondrial Plasticity Underlying Nervous System Diseases, National Demonstration Center for Experimental Preclinical Medicine Education, Xi'an, 710032, China.
Yulu Xia *School of Basic Medical Sciences, Fourth Military Medical University, Laboratory of Mitochondrial Plasticity Underlying Nervous System Diseases, National Demonstration Center for Experimental Preclinical Medicine Education, Xi'an, 710032, China.
Ziwei NiSchool of Medicine, Yan'an University, Yan'an, 716000, China.
Changlei ZhuSchool of Basic Medical Sciences, Fourth Military Medical University, Laboratory of Mitochondrial Plasticity Underlying Nervous System Diseases, National Demonstration Center for Experimental Preclinical Medicine Education, Xi'an, 710032, China.
Kunlong ZhangDepartment of Rehabilitation and Physical Therapy, First Affiliated Hospital of Fourth Military Medical University, Xi'an, 710032, China.
Bozhi LiuSchool of Basic Medical Sciences, Fourth Military Medical University, Laboratory of Mitochondrial Plasticity Underlying Nervous System Diseases, National Demonstration Center for Experimental Preclinical Medicine Education, Xi'an, 710032, China.
Rui LinSchool of Basic Medical Sciences, Fourth Military Medical University, Laboratory of Mitochondrial Plasticity Underlying Nervous System Diseases, National Demonstration Center for Experimental Preclinical Medicine Education, Xi'an, 710032, China.
Jingxuan ZhuSchool of Basic Medical Sciences, Fourth Military Medical University, Laboratory of Mitochondrial Plasticity Underlying Nervous System Diseases, National Demonstration Center for Experimental Preclinical Medicine Education, Xi'an, 710032, China.
Hui LiuSchool of Basic Medical Sciences, Fourth Military Medical University, Laboratory of Mitochondrial Plasticity Underlying Nervous System Diseases, National Demonstration Center for Experimental Preclinical Medicine Education, Xi'an, 710032, China.
Shujiao LiSchool of Basic Medical Sciences, Fourth Military Medical University, Laboratory of Mitochondrial Plasticity Underlying Nervous System Diseases, National Demonstration Center for Experimental Preclinical Medicine Education, Xi'an, 710032, China.
Yunqiang HuangSchool of Basic Medical Sciences, Fourth Military Medical University, Laboratory of Mitochondrial Plasticity Underlying Nervous System Diseases, National Demonstration Center for Experimental Preclinical Medicine Education, Xi'an, 710032, China.
Feifei WuSchool of Basic Medical Sciences, Fourth Military Medical University, Laboratory of Mitochondrial Plasticity Underlying Nervous System Diseases, National Demonstration Center for Experimental Preclinical Medicine Education, Xi'an, 710032, China.
Nannan LiuSchool of Basic Medical Sciences, Fourth Military Medical University, Laboratory of Mitochondrial Plasticity Underlying Nervous System Diseases, National Demonstration Center for Experimental Preclinical Medicine Education, Xi'an, 710032, China.
Shuai ZhangSchool of Basic Medical Sciences, Fourth Military Medical University, Laboratory of Mitochondrial Plasticity Underlying Nervous System Diseases, National Demonstration Center for Experimental Preclinical Medicine Education, Xi'an, 710032, China.
Yousheng WuSchool of Basic Medical Sciences, Fourth Military Medical University, Laboratory of Mitochondrial Plasticity Underlying Nervous System Diseases, National Demonstration Center for Experimental Preclinical Medicine Education, Xi'an, 710032, China.
Fei TianSchool of Basic Medical Sciences, Fourth Military Medical University, Laboratory of Mitochondrial Plasticity Underlying Nervous System Diseases, National Demonstration Center for Experimental Preclinical Medicine Education, Xi'an, 710032, China.
Yanling YangDepartment of Hepatobiliary Surgery, First Affiliated Hospital of Fourth Military Medical University, Xi'an, 710032, China. yangyanl@fmmu.edu.cn.ORCID http://orcid.org/0000-0001-8246-1756
Yayun WangSchool of Basic Medical Sciences, Fourth Military Medical University, Laboratory of Mitochondrial Plasticity Underlying Nervous System Diseases, National Demonstration Center for Experimental Preclinical Medicine Education, Xi'an, 710032, China. wangyy@fmmu.edu.cn.ORCID http://orcid.org/0000-0002-0397-0390

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Approximately 40% of the global population experiences at least one syncope episode during their lifetime. However, the neurobiological mechanisms underlying these effects remain unclear. In this study, facial administration of formalin in mice was used to induce painful syncope. Whole-brain atlas analysis of 116,283 c-Fos

Indexed as

CoordinationMitochondrial networksNeuronal activationPainful syncopeTRAP2-MITO-GFP miceTRAP2-tdTomato mice

Identifiers

PMID42399592

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.