Evidence map›Paper›PMID 42399525›Full record

ArticleNeurology and therapy2026

Neurologists' Views on the Management of Uncontrolled Epilepsy in Spain: A Preliminary Survey.

Luis Lobato, Javier Riancho, David García-Azorín, Paloma Pérez-Domper, Ángel Aledo-Serrano, Juan J Poza

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Article in Neurology and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Luis Lobato *Hospital Puerta del Mar, Cádiz, Andalusia, Spain.
Javier Riancho *Hospital General Sierrallana-IDIVAL, Torrelavega, Spain.ORCID http://orcid.org/0000-0001-7929-1055
David García-AzorínDepartment of Neurology, Hospital Universitario del Río Hortega, Valladolid, Castile and Leon, Spain. davilink@hotmail.com.ORCID http://orcid.org/0000-0002-3132-1064
Paloma Pérez-DomperAngelini Pharma, Barcelona, Spain.ORCID http://orcid.org/0000-0002-5839-1775
Ángel Aledo-Serrano *Clinical Neurosciences Institute, Blua Sanitas Valdebebas University Hospital, Madrid, Spain.ORCID http://orcid.org/0000-0003-4889-3365
Juan J Poza *Department of Neurology, Donostia University Hospital, Donostia-San Sebastián, Spain.ORCID http://orcid.org/0000-0001-8610-1467

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionUncontrolled epilepsy is a major societal burden with significant impacts on patients' health and quality of life. This study evaluated neurologists' practices and perceptions in managing uncontrolled epilepsy in Spain.

methodsIn this observational study, an anonymous, online, 23-item, qualitative survey was distributed to neurologists practising in Spain. Topics included demographics, perceptions of seizure control, knowledge of antiseizure medications (ASM) and clinical practices. Responses were analysed using descriptive statistics.

resultsA total of 127 participants (33 epilepsy specialists, 94 non-specialists) completed the survey; 114 of the 127 respondents (90%) had at least 5 years' experience in managing people with epilepsy. Among the 127 respondents, 76% (88% of specialists; 71% of non-specialists) defined controlled epilepsy as freedom from all seizures and 60% considered persistence of some seizures to be acceptable-at least to some extent. Ninety respondents (71%) reported having 16-30 min available for initial consultations with patients and 89 (70%) had 0-15 min available for follow-up consultations; 125 (98%) indicated that time constraints in consultations impact follow-up care. In terms of clinical experience/familiarity with ASM, epilepsy specialists were significantly more familiar with perampanel (p < 0.05), clobazam (p < 0.001), zonisamide (p < 0.05), cenobamate (p < 0.001), ethosuximide (p < 0.001), cannabidiol (p < 0.001), rufinamide (p < 0.001) and fenfluramine (p < 0.001) than non-specialists. The main challenges reported by the respondents when selecting a drug for uncontrolled epilepsy included 'adverse events' (57%), 'a preference for drugs in which they have more experience' (53%) and 'difficulty in keeping up to date with new medicines' (31%).

conclusionThere is a discrepancy between neurologists' treatment goals and their acceptance of persistent seizures in Spanish neurological practice. Several factors may be limiting the achievement of early seizure freedom, including short patient consultations and a lack of familiarity with new treatments, especially among epilepsy non-specialists. Addressing these barriers could improve outcomes for people with uncontrolled epilepsy.

Indexed as

Antiseizure medicationConsultationsFollow upNon-adherenceSeizures

Identifiers

PMID42399525
PMCPMC13615217

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.