Evidence map›Paper›PMID 42399432›Full record

ArticleLangenbeck's archives of surgery2026

Triangular anastomosis enhances early patency of small middle hepatic vein tributaries in right lobe living donor liver transplantation.

Chi-Yi Chen, Qi-Ming Zheng, Ji-San Sun, Yan Xie, Hong-Hai Wang, Qing-Jun Guo, Li Zhang, Wen-Tao Jiang

Abstract readComparative Study
In one paragraph

Article in Langenbeck's archives of surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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8 authors.

Chi-Yi ChenDepartment of Liver Transplantation, Tianjin First Central Hospital, Tianjin, 300192, China.
Qi-Ming ZhengDepartment of Liver Transplantation, Tianjin First Central Hospital, Tianjin, 300192, China.
Ji-San SunDepartment of Liver Transplantation, Tianjin First Central Hospital, Tianjin, 300192, China.
Yan XieDepartment of Liver Transplantation, Tianjin First Central Hospital, Tianjin, 300192, China.
Hong-Hai WangDepartment of Liver Transplantation, Tianjin First Central Hospital, Tianjin, 300192, China.
Qing-Jun GuoDepartment of Liver Transplantation, Tianjin First Central Hospital, Tianjin, 300192, China. 13752038251@163.com.
Li ZhangDepartment of Liver Transplantation, Tianjin First Central Hospital, Tianjin, 300192, China. tjzhli@126.com.
Wen-Tao JiangDepartment of Liver Transplantation, Tianjin First Central Hospital, Tianjin, 300192, China. jiangwentao@nankai.edu.cn.

Funding

Independent Research Fund of the Institute of Transplant Medicine at Nankai University Grant No.NKTM2023004Key Project of Tianjin Science and Technology Bureau Applied Basic Research Grant No.23JCZDJC01200Tianjin Key Medical Discipline Construction Project Grant No.TJYXZDXK-3-006A-1
6 · The paper itself

Abstract

backgroundIn right-lobe living donor liver transplantation (LDLT) without middle hepatic vein (MHV) inclusion, conventional anastomosis results in poor early patency of MHV tributaries ≤ 5 mm, which may cause graft congestion and dysfunction, especially in recipients with marginal graft-to-recipient weight ratio (GRWR). This study evaluated the safety and efficacy of a novel triangular anastomosis for small MHV tributary reconstruction.

methodsA single-center, two-period comparative study enrolled 42 adult LDLT recipients (May 2019-December 2025). Period 1 (2019-2023) comprised 24 patients undergoing conventional anastomosis; Period 2 (2023-2025) included 18 patients receiving triangular anastomosis for MHV tributaries ≤ 5 mm (standard reconstruction for > 5 mm). Primary endpoint was 7-day patency of ≤ 5 mm tributaries; secondary endpoints included graft function, complications, and 1-year survival. Patency was analyzed by generalized estimating equations (GEE), and survival by Kaplan-Meier method.

resultsBaseline and intraoperative characteristics were well balanced. The 7-day patency of ≤ 5 mm tributaries was significantly higher in Period 2 (75.0% vs. 26.7%, GEE-adjusted P = 0.032), with no significant 30-day patency difference. Time to total bilirubin normalization was shorter (7.10 ± 3.28 vs. 11.17 ± 3.24 days, P = 0.009). Complication and 1-year survival rates were comparable between groups (both P > 0.05).

conclusionsWithin the limitations of this small single-center cohort, triangular anastomosis improves early patency of small MHV tributaries and may contribute to earlier graft functional recovery without additional risks. It is a safe and feasible option for high-risk small venous reconstruction in MHV-excluded right-lobe LDLT with marginal GRWR. However, these findings are preliminary, and larger studies with longer follow-up are needed to confirm long-term efficacy.

Indexed as

Anastomosis, SurgicalHepatic VeinsLiver TransplantationLiving DonorsVascular PatencyAdultFemaleHumansMaleMiddle AgedRecipient VesselsRetrospective StudiesTreatment OutcomeLiver transplantationLiving donorMiddle hepatic veinSmall-for-size syndromeTriangular anastomosisVenous reconstruction

Identifiers

PMID42399432
PMCPMC13627178

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.