Evidence map›Paper›PMID 42399375›Full record

ArticleCommunications medicine2026

Troponin release and mechanism-dependent myocardial injury in a lightning-induced mass casualty incident.

Marcin Waligóra, Tomasz Sanak, Maciej Mikiewicz, Ryan Blumenthal, Klaudia Zaczyńska, Sylweriusz Kosiński, Giewont’2019 MCI Review Group

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Article in Communications medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Marcin Waligóra *Department of Cardiac and Vascular Diseases, St. John Paul II Hospital, Kraków, Poland.
Tomasz Sanak *Department of Disaster and Emergency Medicine, Jagiellonian University Medical College, Kraków, Poland. sanaktomek@gmail.com.
Maciej MikiewiczCenter for Intensive Care and Perioperative Medicine, Jagiellonian University Medical College, Kraków, Poland.
Ryan BlumenthalDepartment of Forensic Medicine, University of Pretoria, Pathology Building, 5 Bophelo Road, Prinshof South Campus, Pretoria, South Africa.ORCID http://orcid.org/0000-0002-5023-6084
Klaudia ZaczyńskaDepartment of Cardiac and Vascular Diseases, St. John Paul II Hospital, Kraków, Poland.
Sylweriusz KosińskiTatra Mountain Rescue Service, Zakopane, Poland.
Giewont’2019 MCI Review Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSystematic data on cardiac involvement after lightning strikes are limited and mostly derived from case reports. On 22 August 2019, a cloud-to-ground lightning event on Mt. Giewont (Poland) caused a mass casualty incident, providing a unique opportunity to characterize myocardial injury in a large cohort. This study aimed to quantify high-sensitivity cardiac troponin (hs-cTnT) release after lightning strike and its relationship with injury mechanisms.

methodsIndividuals from the MT Giewont incident with available troponin measurements were analyzed. Injury mechanisms were predefined, and the location on the trail at the time of the strike was determined. Peak hs-cTnT measured in the emergency department was the primary biomarker of myocardial injury. Among 131 exposed hikers, 59 underwent hs-cTnT testing. The cohort comprised 27 (45.8%) females, and median age of individuals was 29.5 years (IQR 23-41).

resultsOverall, 27 (45.8%) exceeded the upper reference limit of hs-cTnT (URL; 14 ng/L). Median peak hs-cTnT was 13 ng/L (IQR 7.6-25.6). Individuals with direct strike/side-flash exposure had significantly greater troponin levels (median 25.6 vs 10.7 ng/L; p = 0.004). In multivariable analysis, direct/side flash exposure was the only independent predictor of increased troponin (β = 0.90 p = 0.014; relative change +146%). Contact injury, ground current, and blast injury were not significant. ECG abnormalities were uncommon despite frequent biomarker elevation. Individuals with hs-cTnT above the upper reference limit were more frequently admitted to hospital (63% vs 34.4%; p = 0.03), with a 60% increase in odds of admission per doubling of troponin (95% CI 1.01-2.5; p = 0.048). Discrimination for admission was moderate (AUC 0.66, 95% CI 0.52-0.78); a threshold >16 ng/L provided 53.6% sensitivity and 77.4% specificity.

conclusionsAmong individuals who underwent cardiac troponin testing, nearly half demonstrated elevated hs-cTnT levels. Troponin release was significantly greater in individuals exposed to direct strike/side flash.

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.