Evidence map›Paper›PMID 42399127›Full record

Trial reportInjury2026

Cumulative traumatic life events and increased risk for emergency department and inpatient utilization after physical injury hospitalization.

Mary Huynh, Stephen O'Connor, Megan McManamen, Allison Engstrom Buggaveeti, Joan Russo, Jin Wang, Matthew Iles-Shih, Jake Shoyer, Lauren Whiteside, Douglas Zatzick

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Injury, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mary HuynhDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, USA.
Stephen O'ConnorPsychiatry and Neurobehavioral Sciences, University of Virginia School of Medicine, Charlottesville, VA, USA.
Megan McManamenDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, USA.
Allison Engstrom BuggaveetiDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, USA.
Joan RussoDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, USA.
Jin WangDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, USA.
Matthew Iles-ShihDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, USA.
Jake ShoyerDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, USA.
Lauren WhitesideDepartment of Emergency Medicine, University of Washington School of Medicine, Seattle, WA, USA.
Douglas ZatzickDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, USA. Electronic address: dzatzick@uw.edu.

Funding

A Deployment Focused Pragmatic Trial of Optimal Stepped Care Intervention Targeting PTSD and Comorbidity for Acutely Hospitalized Injury Survivors Treated in US Trauma Care SystemsR01MH130460 · NIMH · UNIVERSITY OF WASHINGTON · PI EILEEN M BULGER, DOUGLAS F ZATZICK · 2022 to 2026
$3.8M
NIMH NIH HHS R01 MH130460
6 · The paper itself

Abstract

introductionFew large-scale investigations have examined the association between the cumulative burden of traumatic life events and population-based assessments of emergency department (ED) and inpatient utilization among physically injured trauma survivors.

methodsThe investigation was a secondary analysis of a randomized clinical trial that examined the association between cumulative traumatic life events and ED/inpatient utilization after physical injury hospitalization. All 445 physically injured trauma survivors included in the investigation were aged ≥ 18 and underwent screening for elevated posttraumatic stress symptoms. Three types of patient characteristics were examined for potential significant associations with the longitudinal ED/inpatient utilization outcome: pre-injury, baseline at the time of index physical injury admission, and events that occurred in the year post-injury. Regression analyses were used to assess the association between these clinical and demographic characteristics and ED/inpatient utilization in the 12-36 months after the index injury admission.

resultsApproximately one-third of patients reported ≥ 7 serious traumatic life events before the index injury admission. Approximately 62% of patients had one or more ED/inpatient visits over the course of the 12-36 months post-injury. Clinical and demographic characteristics that were significantly associated with ED/inpatient visits were ≥ 7 prior traumas (Odds Ratio [OR] = 1.35, 95% Confidence Interval [CI] = 1.02, 1.78), pre-injury ED visits (OR = 2.42, CI = 1.85, 3.15), lower educational attainment (OR = 1.41, CI = 1.08, 1.86), and traumatic life events in the year following injury admission (OR = 2.53, CI = 1.72, 3.73).

conclusionIn a cohort of hospitalized physically injured trauma survivors, both pre-injury and post-injury traumatic life events were associated with an increased risk of ED/inpatient utilization. Pre- and post-injury traumatic life events retained their association with increased utilization even after adjusting for relevant clinical and demographic characteristics. Future investigations examining health service use after traumatic injury could be conducted in more generalizable samples of injury survivors and also could productively incorporate assessments of cumulative lifetime trauma burden. Such research could further explore the relationships between lifetime trauma history, post-traumatic stress symptoms, functional impairments, and health service utilization in order to develop effective interventions for diverse trauma survivors.

Indexed as

Emergency Service, HospitalHospitalizationLife Change EventsStress Disorders, Post-TraumaticSurvivorsWounds and InjuriesAdultEmergency Room VisitsFemaleHumansMaleMiddle AgedRisk FactorsEmergency Department UtilizationLifetime Trauma HistoryPopulation-based Outcome AssessmentPosttraumatic Stress DisorderSocial Determinants of HealthTrauma Center

Identifiers

PMID42399127
PMCPMC13384422

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.