Evidence map›Paper›PMID 42398981›Full record

ArticleBMJ case reports2026

Unmasking a rare contrast reaction: acute non-cardiogenic pulmonary oedema after iohexol injection.

Cecil Maria Jose, Naveen Gamini, Sabarish B Nair, Bharath Prasad, Gireesh Kumar

Abstract readCase Reports
In one paragraph

Article in BMJ case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Cecil Maria JoseEmergency Medicine, Amrita Vishwa Vidyapeetham Amrita Health Sciences Campus, Kochi, Kerala, India annacecil@gmail.com.ORCID http://orcid.org/0009-0003-5912-8818
Naveen GaminiEmergency Medicine, Amrita Vishwa Vidyapeetham Amrita Health Sciences Campus, Kochi, Kerala, India.
Sabarish B NairEmergency Medicine, Amrita Vishwa Vidyapeetham Amrita Health Sciences Campus, Kochi, Kerala, India.
Bharath PrasadEmergency Medicine, Amrita Vishwa Vidyapeetham Amrita Health Sciences Campus, Kochi, Kerala, India.
Gireesh KumarAmrita Vishwa Vidyapeetham Amrita Health Sciences Campus, Kochi, Kerala, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A woman with multiple comorbidities developed acute respiratory distress within minutes of intravenous iohexol administration for abdominal imaging. She presented with severe hypoxaemia, bilateral pulmonary crackles and diffuse opacities on chest imaging without evidence of cardiac dysfunction. Bedside echocardiography and brain natriuretic peptide levels excluded cardiogenic pulmonary oedema. A diagnosis of contrast-induced non-cardiogenic pulmonary oedema was made. She required non-invasive ventilation and supportive therapy with complete resolution over 1 week. This case highlights a rare, life-threatening but reversible reaction to iodinated contrast and underscores the importance of early recognition, prompt respiratory support and readiness with resuscitation equipment during contrast administration.

Indexed as

Contrast MediaIohexolPulmonary EdemaEchocardiographyFemaleHumansNoninvasive VentilationContrast MediaIohexolCardiovascular systemContraindications and precautionsHypersensitivityIncidenceRespiratory system

Identifiers

PMID42398981
PMCPMC13342689

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.