Evidence map›Paper›PMID 42397686›Full record

SynthesisActa paediatrica (Oslo, Norway : 1992)2026

Prevalence of Breastfeeding in Infants With Down Syndrome: A Systematic Review and Meta-Analysis.

Mélina Balland, Julia Prillard, Irène Loras-Duclaux, Caroline Giroudon, Amélie Zelmar, Damien Sanlaville, Mikail Nourredine

Abstract readSystematic ReviewMeta-AnalysisReview
In one paragraph

Synthesis in Acta paediatrica (Oslo, Norway : 1992), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mélina BallandHospices Civils de Lyon, Lyon, France.ORCID https://orcid.org/0009-0003-8889-7819
Julia PrillardHospices Civils de Lyon, Lyon, France.
Irène Loras-DuclauxHospices Civils de Lyon, Hôpital Femme Mère Enfant, Service d'hépato-gastro-entérologie et nutrition pédiatrique, Bron, France.
Caroline GiroudonHospices Civils de Lyon, Service de la Documentation Centrale, TAC, Lyon, France.ORCID https://orcid.org/0000-0001-7947-9437
Amélie ZelmarService Recherche et Epidémiologie Cliniques, Pôle de Santé Publique, Hospices Civils de Lyon, Lyon, France.
Damien SanlavilleHospices Civils de Lyon, Service de Génétique, Lyon, France.
Mikail NourredineHospices Civils de Lyon, Service de Biostatistique-Bioinformatique, Lyon, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo estimate the prevalence of breastfeeding-overall, exclusive, partial and depending on infants' age-in infants with Down syndrome, and to investigate associated factors.

methodsA systematic literature search was conducted in Medline, Cochrane Library, Web of Science, Embase, CINAHL and SciELO up to 1 August 2024. Original articles that estimated the prevalence of breastfeeding in infants with Down syndrome, written in French, English or Spanish, were included. Study quality was assessed using the Joanna Briggs Institute (JBI) scale. Meta-analyses were performed for breastfeeding outcomes and meta-regression explored heterogeneity. The review was registered in PROSPERO (CRD42021278019).

resultsTwenty-six studies (3463 infants) were included. The estimated prevalence of overall breastfeeding regardless of duration was 71.6% (95% CI [60.3; 80.7]; 25 studies, 3351 infants) with high heterogeneity, I

conclusionThe estimated breastfeeding prevalence in infants with Down syndrome is similar to that reported in the general population, despite high heterogeneity. Further studies using standardised methodology to assess breastfeeding barriers and facilitators in the context of Down syndrome would allow us to improve support for breastfeeding.

Indexed as

Breast FeedingDown SyndromeHumansInfantInfant, NewbornPrevalencebreastfeedingDown syndromefeeding behaviourmeta‐analysissystematic review

Identifiers

PMID42397686
PMCPMC13552598

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.