Evidence map›Paper›PMID 42397621›Full record

ArticleUpdates in surgery2026

Algorithms for management of patients with iatrogenic bile duct injury: a single-center experience.

Mohammad Mehdi Lashkarizadeh, Reyhaneh Naseri, Raha Shahrokhi, Mohammad Sadegh Rajabian, Kasra Assadian, Sara Farifteh, Ali Reza Shamsaeefar, Kourosh Kazemi, Behrouz Seydi Majd, Mehran Jafari and 3 more

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Article in Updates in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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13 authors.

Mohammad Mehdi LashkarizadehShiraz Transplant Center, Abu-Ali-Sina Hospital, Shiraz University of Medical Sciences, Shiraz, 7199467985, Iran.
Reyhaneh NaseriSchool of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Raha ShahrokhiSchool of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Mohammad Sadegh RajabianDepartment of Surgery, School of medicine, Shiraz University of Medical Science, Shiraz, Iran.
Kasra AssadianSchool of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Sara FariftehShiraz Transplant Center, Abu-Ali-Sina Hospital, Shiraz University of Medical Sciences, Shiraz, 7199467985, Iran.
Ali Reza ShamsaeefarShiraz Transplant Center, Abu-Ali-Sina Hospital, Shiraz University of Medical Sciences, Shiraz, 7199467985, Iran.
Kourosh KazemiShiraz Transplant Center, Abu-Ali-Sina Hospital, Shiraz University of Medical Sciences, Shiraz, 7199467985, Iran.
Behrouz Seydi MajdShiraz Transplant Center, Abu-Ali-Sina Hospital, Shiraz University of Medical Sciences, Shiraz, 7199467985, Iran.
Mehran JafariShiraz Transplant Center, Abu-Ali-Sina Hospital, Shiraz University of Medical Sciences, Shiraz, 7199467985, Iran.
Ahmad Khalid SanaeiShiraz Transplant Center, Abu-Ali-Sina Hospital, Shiraz University of Medical Sciences, Shiraz, 7199467985, Iran.
Shamim AfshinmehrDepartment of Radiology, School of medicine, Kerman Medical University, Kerman, Iran.
Hamed NikoupourShiraz Transplant Center, Abu-Ali-Sina Hospital, Shiraz University of Medical Sciences, Shiraz, 7199467985, Iran. nikoupour@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Iatrogenic bile duct injury (BDI) remains a serious complication and global health problem with high morbidity, posing challenges for diagnosis and management. This study aims to evaluate the effectiveness of management algorithms for BDIs and assess the clinical outcomes at a single tertiary referral center. A retrospective, cross-sectional study was conducted on 142 patients diagnosed with iatrogenic BDI from July 2017 to January 2024. Management algorithms were developed based on intra- and postoperative decision points, including patient condition, timing of repair, and referral to specialized centers. Clinical outcomes including postoperative complications and anastomotic stricture rates were analyzed. Of the 142 patients (mean age of 46.76 ± 15.03 years, 66.9% women), 26.1% diagnosed intraoperatively, while the majority were identified postoperatively based on subjective symptoms (abdominal pain, jaundice) or objective signs (bile leakage from a surgical drain). The most common injury type was type E (85.7%). A total of 7.74% required ICU admission, and there was no perioperative mortality. Associated injuries were common, with right hepatic artery injury occurring in 19.7% of cases and a few patients (2.1%) experienced combined hepatic artery and portal vein injuries that three of them required hepatectomy and one patient required liver transplantation. Postoperative complications, including anastomotic stricture, were notably lower compared to the literature. The majority of BDIs were repaired with hepaticojejunostomy, and the outcomes were favorable, even in re-operated patients that initially repaired by the index surgeon and no significant difference was observed in long-term outcomes of both groups. It suggests that optimal timing of operation is crucial for success. Our study highlights the importance of a structured, algorithm-based approach in the management of iatrogenic BDIs. Early referral to a specialized hepatobiliary center, timely intervention, and the use of hepaticojejunostomy significantly reduce postoperative complications and improve outcomes.

Indexed as

Bile duct injuryHepatectomyHepaticojejunostomyLiver transplantRight hepatic artery

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.