Evidence map›Paper›PMID 42397560›Full record

ArticleSurgery today2026

Clinical significance of lower admission amylase levels as an indicator of medical management in pancreatic trauma with AAST grade I injury.

Kyohei Matsumoto, Atsushi Shimizu, Akihiro Takeuchi, Hideki Motobayashi, Masatoshi Sato, Tomohiro Yoshimura, Shinya Hayami, Atsushi Miyamoto, Kensuke Nakamura, Manabu Kawai

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Article in Surgery today, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kyohei MatsumotoSecond Department of Surgery, School of Medicine, Wakayama Medical University, 811-1, Kimiidera, Wakayama, 641-8510, Japan.
Atsushi ShimizuSecond Department of Surgery, School of Medicine, Wakayama Medical University, 811-1, Kimiidera, Wakayama, 641-8510, Japan.
Akihiro TakeuchiSecond Department of Surgery, School of Medicine, Wakayama Medical University, 811-1, Kimiidera, Wakayama, 641-8510, Japan.
Hideki MotobayashiSecond Department of Surgery, School of Medicine, Wakayama Medical University, 811-1, Kimiidera, Wakayama, 641-8510, Japan.
Masatoshi SatoSecond Department of Surgery, School of Medicine, Wakayama Medical University, 811-1, Kimiidera, Wakayama, 641-8510, Japan.
Tomohiro YoshimuraSecond Department of Surgery, School of Medicine, Wakayama Medical University, 811-1, Kimiidera, Wakayama, 641-8510, Japan.
Shinya HayamiSecond Department of Surgery, School of Medicine, Wakayama Medical University, 811-1, Kimiidera, Wakayama, 641-8510, Japan.
Atsushi MiyamotoSecond Department of Surgery, School of Medicine, Wakayama Medical University, 811-1, Kimiidera, Wakayama, 641-8510, Japan.
Kensuke NakamuraSecond Department of Surgery, School of Medicine, Wakayama Medical University, 811-1, Kimiidera, Wakayama, 641-8510, Japan.
Manabu KawaiSecond Department of Surgery, School of Medicine, Wakayama Medical University, 811-1, Kimiidera, Wakayama, 641-8510, Japan. kawai@wakayama-med.ac.jp.ORCID http://orcid.org/0000-0003-3506-9895

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe aimed to explore whether the admission serum amylase levels may help inform the selection of medical management in patients with AAST Grade I pancreatic injuries.

methodsWe retrospectively reviewed the records of 20 patients treated for pancreatic trauma between 2010 and 2024. They were categorized into medical management or intervention groups according to the initial treatment strategy. We used a receiver operating characteristic (ROC) analysis to evaluate the predictive value of the admission serum amylase levels for successful medical management.

resultsEight patients were treated with strict medical management, whereas 12 required additional interventions. All patients in the medical management group had AAST Grade I injuries, and none required conversion to interventional treatment. The admission serum amylase levels were significantly lower in the medical management group (median 106 vs. 350 IU/L; p = 0.0228), whereas there were no significant intergroup differences in inflammatory markers. The ROC analysis yielded an area under the curve of 0.83 (95% CI, 0.59- 1.00). The cutoff value was 158 IU/L, with a sensitivity of 87.5% and a negative predictive value of 90.9%.

conclusionLower admission serum amylase levels in patients with AAST Grade I pancreatic injury may be associated with suitability for strict medical management; however, these findings are exploratory and require validation in larger multicenter studies.

Indexed as

AmylasesPancreasAdultBiomarkersClinical RelevanceFemaleHumansMaleMiddle AgedPredictive Value of TestsRetrospective StudiesROC CurveAmylasesBiomarkersAAST Grade IMedical managementPancreatic traumaTraumatic pancreatic injuries

Identifiers

PMID42397560

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.