ArticleSICOT-J2026
Defining the dystrophic femoral neck in osteogenesis imperfecta: a radiographic and anatomical entity with diagnostic threshold.
Article in SICOT-J, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionSevere Osteogenesis Imperfecta (OI) can cause distinct proximal femoral deformities, but specific femoral neck changes remain poorly defined. This study aimed to characterize dystrophic femoral neck morphology and determine a diagnostic threshold.
methodsWe retrospectively reviewed anteroposterior pelvic radiographs from patients >8 years old with severe OI (n = 24 hips) and age-matched controls (n = 24 hips). Measurements included femoral neck length, neck diameter, head diameter, neck-shaft angle, anterior lateral proximal femoral angle (aLPFA), and acetabular protrusion. Ratios of neck length-to-diameter and neck length-to-head diameter were calculated. Statistical comparisons used t-tests; ROC analysis identified the optimal threshold for distinguishing dystrophic necks.
resultsOI patients had shorter femoral necks (52.7 ± 9.9 mm vs. 64.8 ± 9.6 mm, p < 0.001), smaller diameters (19.4 ± 4.7 mm vs. 32.8 ± 4.8 mm, p < 0.0001), and higher neck length-to-diameter ratios (2.82 ± 0.63 vs. 1.98 ± 0.19, p < 0.000001). A threshold of ≥2.35 (AUC = 0.90) identified dystrophic necks, associated with greater acetabular protrusion (-2.91 ± 12.33 mm vs. 4.42 ± 8.67 mm, p = 0.004). DISCUSSION: A neck length-to-diameter ratio ≥ 2.35 reliably defines dystrophic femoral necks in OI and correlates with increased acetabular protrusion. Early recognition may guide surgical planning and help preserve hip function. LEVEL OF EVIDENCE: Level IV - Retrospective comparative study.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.