Evidence map›Paper›PMID 42396881›Full record

ArticleMagnetic resonance in medicine2026

7T 3D-EPI PCASL With High SNR Efficiency and Robustness to Through-Plane B

Gael Saib, Alan P Koretsky, S Lalith Talagala

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Magnetic resonance in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gael SaibLaboratory of Functional and Molecular Imaging, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA.ORCID https://orcid.org/0000-0003-2571-2410
Alan P KoretskyLaboratory of Functional and Molecular Imaging, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA.
S Lalith TalagalaNIH MRI Research Facility, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA.

Funding

Intramural Research Program of the National Institutes of HealthNINDS NIH HHS
6 · The paper itself

Abstract

purpose7T pseudo-continuous arterial spin labeling (PCASL) can benefit from combining 3D-EPI with high-performance background suppression (BS) pulses. However, the perfusion signal can be compromised by increased B

methods7T PCASL SNR efficiency (SNReff) was quantified using a range of LD (500-4000 ms) with optimized BS inversion pulses and 3D-EPI acquisitions. PCASL sensitivity to

resultsOptimized WURST BS pulses achieved ∼0.93 inversion efficiency. PCASL SNReff was maximized when employing a LD of ∼3 s (B

conclusion7T PCASL SNReff can be maximized with LD of ∼3 s when using 3D-EPI and optimized WURST BS pulses. A G

Indexed as

BrainEcho-Planar ImagingImaging, Three-DimensionalAlgorithmsHumansImage EnhancementImage Processing, Computer-AssistedMagnetic Resonance AngiographyPerfusion Magnetic Resonance ImagingPhantoms, ImagingSignal-To-Noise RatioSpin LabelsSpin Labels3D7Toff‐resonance gradientsPCASLsignal‐to‐noise ratioultra‐high field MRI

Identifiers

PMID42396881
PMCPMC13527263

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.