ArticleJournal of the American Heart Association2026
Impact of Intimal Tear Location on Clinical Outcomes in Extensive Arch Repair of Acute Stanford Type A Aortic Dissection.
Yumeng Ji, Chenyu Zhou, Kai Zhang, Wei Gao, Bin Hou, Ji Wang, Shiqi Gao, Kai Xu, Xiaogang Sun, Cuntao Yu and 1 more
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In one paragraphArticle in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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11 authors.
Yumeng Ji *Department of Vascular Surgery National Center for Cardiovascular Diseases, National Clinical Research Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.
Chenyu Zhou *Department of Vascular Surgery National Center for Cardiovascular Diseases, National Clinical Research Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.ORCID 0000-0002-3297-5879 Kai Zhang *Department of Cardiac Surgery Beijing Anzhen Hospital, Capital Medical University, and Beijing Institute of Heart, Lung and Blood Vessel Diseases Beijing China.ORCID 0000-0001-6818-377X Wei GaoDepartment of Vascular Surgery National Center for Cardiovascular Diseases, National Clinical Research Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.
Bin HouDepartment of Vascular Surgery National Center for Cardiovascular Diseases, National Clinical Research Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.
Ji WangDepartment of Vascular Surgery National Center for Cardiovascular Diseases, National Clinical Research Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.
Shiqi GaoDepartment of Vascular Surgery National Center for Cardiovascular Diseases, National Clinical Research Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.
Kai XuDepartment of Vascular Surgery National Center for Cardiovascular Diseases, National Clinical Research Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.
Xiaogang SunDepartment of Vascular Surgery National Center for Cardiovascular Diseases, National Clinical Research Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.ORCID 0000-0002-3975-2408 Cuntao YuDepartment of Vascular Surgery National Center for Cardiovascular Diseases, National Clinical Research Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.ORCID 0000-0001-7874-9052 Juntao QiuDepartment of Vascular Surgery National Center for Cardiovascular Diseases, National Clinical Research Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.ORCID 0009-0004-8162-6802 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
backgroundThe impact of intimal tear location on outcomes in acute Stanford type A aortic dissection remains unclear. This study investigated the impact of different tear locations on early and long-term death in patients undergoing total arch replacement with frozen elephant trunk.
methodsThis single-center retrospective study included 1524 patients with acute Stanford type A aortic dissection who underwent total arch replacement with frozen elephant trunk from January 2010 to December 2022. Patients were stratified by primary entry tear location: ascending aorta (n=857 [56.2%]), aortic arch (n=459 [30.1%]), and descending aorta (n=208 [13.6%]). Primary end points were in-hospital death and long-term survival. Multivariable regression analyses with further sensitivity analyses for early and long-term outcomes were performed.
resultsIn-hospital death differed significantly among groups (
conclusionsIntimal tear location significantly impacts acute Stanford type A aortic dissection prognosis. Descending aortic tears confer substantially higher early and long-term mortality rates, requiring aggressive perioperative management and closer surveillance. Tear location should be incorporated into risk stratification systems for individualized treatment planning.
Indexed as
Aorta, ThoracicAortic DissectionBlood Vessel Prosthesis ImplantationDissection, Ascending AortaTunica IntimaAgedAortic Aneurysm, ThoracicFemaleHospital MortalityHumansMaleMiddle AgedRetrospective StudiesRisk FactorsTime FactorsTreatment Outcomeacute Stanford type A aortic dissectiondeathfrozen elephant trunkintimal tear locationtotal arch replacement
Identifiers
PMID42396809
PMCPMC13477375
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