Evidence map›Paper›PMID 42396552›Full record

ArticlePCN reports : psychiatry and clinical neurosciences2026

Carbonyl stress markers are associated with binge-eating/purging behavior of anorexia nervosa: A pilot study.

Kana Morimoto, Masanori Isobe, Tomomi Noda, Keima Tose, Momo Sunada, Koichi Tabata, Momoka Taniguchi, Makoto Arai, Toshiya Murai

Abstract read
In one paragraph

Article in PCN reports : psychiatry and clinical neurosciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kana MorimotoDepartment of Psychiatry Kyoto University Graduate School of Medicine Kyoto Japan.ORCID https://orcid.org/0000-0002-3376-7940
Masanori IsobeDepartment of Psychiatry Kyoto University Graduate School of Medicine Kyoto Japan.
Tomomi NodaDepartment of Psychiatry Kyoto University Graduate School of Medicine Kyoto Japan.
Keima ToseDepartment of Psychiatry Kyoto University Graduate School of Medicine Kyoto Japan.
Momo SunadaDepartment of Psychiatry Kyoto University Graduate School of Medicine Kyoto Japan.
Koichi TabataSchizophrenia Research Project, Department of Psychiatry and Behavioral Sciences Tokyo Metropolitan Institute of Medical Science Tokyo Japan.
Momoka TaniguchiDepartment of Psychiatry Kyoto University Graduate School of Medicine Kyoto Japan.
Makoto AraiSchizophrenia Research Project, Department of Psychiatry and Behavioral Sciences Tokyo Metropolitan Institute of Medical Science Tokyo Japan.
Toshiya MuraiDepartment of Psychiatry Kyoto University Graduate School of Medicine Kyoto Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: Anorexia nervosa (AN) is a severe psychiatric disorder causing life-threatening physical conditions. Management strategies differ between the restricting subtype (ANR) and the binge-eating/purging subtype (ANBP), with underreported binge-eating/purging behaviors. Objective biomarkers are needed to detect these behaviors for improved treatment. This study explored fingertip autofluorescence (FAF) Advanced Glycation End Products (AGEs), reflecting carbonyl stress, to assess their potential in reflecting binge-eating/purging behavior in AN. Methods: This cross-sectional study involved 26 female patients with AN and 27 healthy control (HC) participants. Participants completed the Eating Disorder Examination Questionnaire 6.0 (EDE-Q 6.0) and underwent percutaneous fluorescence measurement of AGE levels. Statistical analysis included one-way anova with Tukey's Honestly Significant Difference (HSD) test, Pearson correlation, and multiple linear regression to determine if EDE-Q items predicted fingertip AGE levels in patients with ANBP. Results: Fingertip AGE levels and all EDE-Q 6.0 subscale scores significantly differed among groups ( Conclusion: Fingertip AGE levels were higher in patients with ANBP than in those with ANR. Purging behavior, which was significantly correlated with binge-eating behavior in the ANBP group, was suggested to be a primary determinant of elevated AGE levels. Fingertip AGE levels may serve as objective biomarkers for detecting these behaviors and facilitating improved treatment strategies.

Indexed as

Advanced Glycation End Products (AGEs)ageinganorexia nervosacarbonyl stresspurging

Identifiers

PMID42396552
PMCPMC13324242

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.