Evidence map›Paper›PMID 42396479›Full record

ArticleResearch square2026

Complete Digital Disconnection as a Prognostic Marker of Mortality or Residential-Care Transition in Older Adults With Cardiovascular Risk: A Nationally Representative Cohort Study.

Peng Liu, Ruilong Gao, Yaliu Yang, Zhengqin Zhai, Yifeng Zhou

Abstract readPreprint
In one paragraph

Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Peng LiuChina-Japan Friendship Hospital.
Ruilong GaoChina-Japan Friendship Hospital.
Yaliu YangChina-Japan Friendship Hospital.
Zhengqin ZhaiChina-Japan Friendship Hospital.
Yifeng ZhouChina-Japan Friendship Hospital.

Funding

The National Health and Trends StudyU01AG032947 · NIA · JOHNS HOPKINS UNIVERSITY · PI VICKI A. FREEDMAN, JENNIFER ANN SCHRACK · 2008 to 2026
$169.4M
NIA NIH HHS U01 AG032947
6 · The paper itself

Abstract

Background: Routine health care increasingly requires digital access for appointment scheduling, medication refills, test-result review, clinician messaging, remote monitoring, and telehealth. For older adults with cardiovascular-risk conditions, complete internet disconnection may indicate accumulated geriatric vulnerability and barriers to continuous care. We examined whether complete digital disconnection was associated with mortality or residential-care transition and whether the risk gradient was driven by connectivity rather than telehealth use. Methods: We constructed staggered-entry prospective cohorts using rounds 11-14 of the National Health and Aging Trends Study (2021-2025). Community-dwelling Medicare beneficiaries aged ≥65 years with hypertension, heart disease, or diabetes entered the cohort in round 11, 12, or 13 and were followed through round 14. Digital integration was categorized as telehealth use, connected non-use, or complete disconnection. Outcomes were all-cause mortality and a composite of death or transition to nursing-home or residential care. The primary analysis used survey-weighted discrete-time survival models with entry-cohort fixed effects and participant-level cluster-robust variance estimation. Models were sequentially adjusted for demographic, socioeconomic, health, frailty-related, and geriatric-vulnerability factors. Robustness was assessed using multiple imputation, competing-risks models, E-values, and sensitivity analyses addressing reverse causation. Results: Among 12,139 person-baseline observations from 6,530 adults, the survey-weighted prevalence of complete disconnection was 29.7%. Compared with non-disconnected participants, completely disconnected adults had a higher unadjusted risk of the composite outcome; after adjustment for health and frailty-related factors, the association attenuated but persisted (composite hazard ratio [HR], 1.39; 95% CI, 1.12-1.73; mortality HR, 1.50; 95% CI, 1.16-1.94). The survey-weighted 3-year absolute risk difference was 12.1 percentage points. Telehealth users and connected non-users had similar adjusted risks (composite HR, 0.99; 95% CI, 0.79-1.24). Associations weakened after adjustment for functional status and exclusion of first-interval events. Conclusions: Complete digital disconnection was a reproducible and readily measured prognostic marker of mortality or residential-care transition among older adults with cardiovascular-risk conditions. These findings support a prognostic rather than causal interpretation. Age-friendly digital care should preserve offline-accessible pathways for older adults who remain completely disconnected.

Indexed as

agedcardiovascular diseasescohort studiesdigital dividehealth equityinternet usemortalityNational Health and Aging Trends Studyresidential caretelehealth

Identifiers

PMID42396479
PMCPMC13321284

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.