ArticleIJID regions2026
Utility of cerebrospinal fluid multiplex polymerase chain reaction assay in children suspected of meningitis or encephalitis in a tertiary care hospital in Thailand.
Article in IJID regions, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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6 authors.
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Abstract
Background: The BioFire®FilmArray® meningitis/encephalitis panel (ME panel)identifies 14 cerebrospinal fluid (CSF) pathogens. It has not been studied in Thailand,where the epidemiology of central nervous system (CNS) infection may differ from thatof countries with temperate climates. We conducted a study to evaluate theperformance of the ME panel in Thai children. Method: We conducted a prospective study in children suspected of meningitis orencephalitis at the Queen Sirikit National Institute of Child Health in Bangkok, Thailand.In addition to routine tests, CSF was tested simultaneously with an ME panel. Results: Seventy-three children diagnosed with meningitis or encephalitis wereenrolled. Of them, 47 (64.4%) had an infectious etiology, 21 (28.8%) a non-infectiousetiology (mainly immune encephalitis), and 5 had an undetermined etiology. Thirtypatients had pathogens confirmed: 11 bacteria, 5 Conclusion: The ME panel is a reliable tool for supporting the management of CNSinfections due to its high specificity and rapid turnaround time. However, the diversity ofpathogens that cause CNS diseases poses a challenge to its use in tropical countries.
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