Diagnostic Accuracy of Ischemia-modified Albumin in Complicated Appendicitis and Its Comparison with the Conventional Markers: An Observational Study.

Sujatha Mahadevarao Premnath, Ravichandran Ashwin Chand, R Ariganesan, Achu Jacob Philip, Sunil Kumar Nanda, C M Kiran, Dilip Shankar Phansalkar

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Article in International journal of applied & basic medical research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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Sujatha Mahadevarao PremnathDepartment of Biochemistry, Pondicherry Institute of Medical Sciences, Affiliated to Pondicherry University, Kalapet, Puducherry, India.

Ravichandran Ashwin ChandDepartment of General Surgery, Pondicherry Institute of Medical Sciences, Affiliated to Pondicherry University, Kalapet, Puducherry, India.

R AriganesanDepartment of General Surgery, Pondicherry Institute of Medical Sciences, Affiliated to Pondicherry University, Kalapet, Puducherry, India.

Achu Jacob PhilipDepartment of General Surgery, Pondicherry Institute of Medical Sciences, Affiliated to Pondicherry University, Kalapet, Puducherry, India.

Sunil Kumar NandaDepartment of Biochemistry, Pondicherry Institute of Medical Sciences, Affiliated to Pondicherry University, Kalapet, Puducherry, India.

C M KiranDepartment of Pathology, Pondicherry Institute of Medical Sciences, Affiliated to Pondicherry University, Kalapet, Puducherry, India.

Dilip Shankar PhansalkarDepartment of Radiodiagnosis, Pondicherry Institute of Medical Sciences, Affiliated to Pondicherry University, Kalapet, Puducherry, India.

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6 · The paper itself

Abstract

Background: Acute appendicitis is a common emergency, with one-third presenting as complicated cases. Differentiating complicated appendicitis (CA) from uncomplicated appendicitis (UA) is important to decide on intervention. Conventional markers have limitations, while ischemia-modified albumin (IMA), released during ischemia and oxidative stress, may aid in diagnosis. This study evaluates the utility of IMA in distinguishing CA from UA. Materials and Methods: An observational cross-sectional study conducted in a tertiary care hospital on 85 patients over 13 years with acute appendicitis was further divided into CA ( Results: IMA levels were significantly higher in CA 10.90 ± 5.65 μg/mL compared to UA 6.00 ± 2.93 μg/mL ( Conclusion: IMA appears to be an ideal parameter to identify CA; however, larger multicentric studies are required to validate its clinical utility.

Indexed as

Appendicitisbiomarkersischemia-modified albuminneutrophil lymphocyte ratioserum

Identifiers

PMID42396354

DOI10.4103/ijabmr.ijabmr_330_25

PMCPMC13327376

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