Evidence map›Paper›PMID 42396331›Full record

ArticlemedRxiv : the preprint server for health sciences2026

Intrapartum Oxytocin and Maternal Outcomes Following Vaginal and Unscheduled Cesarean Delivery.

Hadas Allouche-Kam, Isha H Arora, Mary C Lee, Jiajia Zhang, Francine Hughes, Sharon Dekel

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hadas Allouche-KamPostpartum Traumatic Stress Disorders Research Program, Department of Psychiatry, Massachusetts General Hospital, Mass General Brigham, Boston, MA.ORCID 0000-0001-8737-3077
Isha H AroraPostpartum Traumatic Stress Disorders Research Program, Department of Psychiatry, Massachusetts General Hospital, Mass General Brigham, Boston, MA.
Mary C LeePostpartum Traumatic Stress Disorders Research Program, Department of Psychiatry, Massachusetts General Hospital, Mass General Brigham, Boston, MA.
Jiajia ZhangPostpartum Traumatic Stress Disorders Research Program, Department of Psychiatry, Massachusetts General Hospital, Mass General Brigham, Boston, MA.
Francine HughesDivision of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Massachusetts General Hospital, Mass General Brigham, Boston, MA.
Sharon DekelPostpartum Traumatic Stress Disorders Research Program, Department of Psychiatry, Massachusetts General Hospital, Mass General Brigham, Boston, MA.

Funding

Defining postpartum PTSD and its implications for maternal wellness and child developmentR01HD108619 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI Sharon Dekel · 2022 to 2026
$3.7M
NICHD NIH HHS R01 HD108619
6 · The paper itself

Abstract

Objective: To examine whether intrapartum synthetic oxytocin exposure for labor induction or augmentation is associated with breastfeeding and postpartum depressive and traumatic stress symptoms. Methods: We studied 1,296 postpartum women who delivered at a single tertiary care center, with assessments from the third trimester through approximately two months postpartum. Intrapartum oxytocin exposure was obtained from electronic medical records. Outcomes included exclusive breastfeeding, postpartum depression, and childbirth-related traumatic stress. Analyses were stratified by delivery mode and adjusted for key maternal and obstetric covariates. Results: Overall, 63.3% of participants received intrapartum oxytocin. Among participants with vaginal delivery, oxytocin exposure was associated with lower exclusive breastfeeding at two months after adjustment (58.2% vs 70.3%; adjusted RR 0.86, 95% CI 0.76-0.97; Conclusion: Intrapartum oxytocin exposure was associated with lower exclusive breastfeeding after vaginal delivery and modestly higher childbirth-related distress after unscheduled cesarean delivery. These findings suggest that oxytocin exposure may mark or contribute to postpartum vulnerability in specific delivery contexts.

Identifiers

PMID42396331
PMCPMC13321336

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.