Evidence map›Paper›PMID 42396316›Full record

ArticlemedRxiv : the preprint server for health sciences2026

Rare protein-coding variation and the genetic architecture of height in >1.4 million individuals.

Jack A Kosmicki, Liron Ganel, Kyoko Watanabe, Tyler Joseph, Sheila M Gaynor, Michael D Kessler, Joshua D Backman, Joelle Mbatchou, Andrey Ziyatdinov, David Blair and 28 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors.

Jack A KosmickiRegeneron Genetics Center, 777 Old Saw Mill River Rd., Tarrytown, New York, USA.
Liron GanelRegeneron Genetics Center, 777 Old Saw Mill River Rd., Tarrytown, New York, USA.
Kyoko WatanabeRegeneron Genetics Center, 777 Old Saw Mill River Rd., Tarrytown, New York, USA.
Tyler JosephRegeneron Genetics Center, 777 Old Saw Mill River Rd., Tarrytown, New York, USA.
Sheila M GaynorRegeneron Genetics Center, 777 Old Saw Mill River Rd., Tarrytown, New York, USA.
Michael D KesslerRegeneron Genetics Center, 777 Old Saw Mill River Rd., Tarrytown, New York, USA.
Joshua D BackmanRegeneron Genetics Center, 777 Old Saw Mill River Rd., Tarrytown, New York, USA.
Joelle MbatchouRegeneron Genetics Center, 777 Old Saw Mill River Rd., Tarrytown, New York, USA.
Andrey ZiyatdinovRegeneron Genetics Center, 777 Old Saw Mill River Rd., Tarrytown, New York, USA.
David BlairRegeneron Genetics Center, 777 Old Saw Mill River Rd., Tarrytown, New York, USA.
Jonas BovijnRegeneron Genetics Center, 777 Old Saw Mill River Rd., Tarrytown, New York, USA.
Niek VerweijRegeneron Genetics Center, 777 Old Saw Mill River Rd., Tarrytown, New York, USA.
Kathie Y SunRegeneron Genetics Center, 777 Old Saw Mill River Rd., Tarrytown, New York, USA.
Chuanyi ZhangRegeneron Genetics Center, 777 Old Saw Mill River Rd., Tarrytown, New York, USA.
Suganthi BalasubramanianRegeneron Genetics Center, 777 Old Saw Mill River Rd., Tarrytown, New York, USA.
Adrián I CamposRegeneron Genetics Center, 777 Old Saw Mill River Rd., Tarrytown, New York, USA.
Alexander W CharneyIcahn School of Medicine at Mount Sinai, New York, New York, USA.
Olle MelanderDepartment of Clinical Science Malmö, Lund University, Malmö, Sweden.
Robert WeinrebHamilton Glaucoma Center, Viterbi Family Department of Ophthalmology and Shiley Eye Institute, University of California San Diego, California, USA.
Jason TorresClinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Pablo Kuri-MoralesInstituto Tecnológico y de Estudios Superiores de Monterrey, Monterrey, Mexico.
Roberto Tapia-ConyerFaculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico.
Jesús Alegre-DíazExperimental Research Unit from the Faculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico.
Jaime BerumenExperimental Research Unit from the Faculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico.
BELIEVE Study Group
Colorado Center for Personalized Medicine - RGC Collaboration
GHS-RGC DiscovEHR Collaboration
Mayo Clinic Project Generation
México City Prospective Study
Penn Medicine BioBank
Regeneron Genetics Center
University of California Los Angeles-RGC ATLAS Collaboration
Aris BarasRegeneron Genetics Center, 777 Old Saw Mill River Rd., Tarrytown, New York, USA.
Luca A LottaRegeneron Genetics Center, 777 Old Saw Mill River Rd., Tarrytown, New York, USA.
Jonathan MarchiniRegeneron Genetics Center, 777 Old Saw Mill River Rd., Tarrytown, New York, USA.
Gonçalo R AbecasisRegeneron Genetics Center, 777 Old Saw Mill River Rd., Tarrytown, New York, USA.
Manuel A R FerreiraRegeneron Genetics Center, 777 Old Saw Mill River Rd., Tarrytown, New York, USA.
Adam E LockeRegeneron Genetics Center, 777 Old Saw Mill River Rd., Tarrytown, New York, USA.

Funding

UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
Phenotypic Diversity in COVID-19UL1TR001878 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2016 to 2025
$102.4M
NCATS NIH HHS UL1 TR001878NCATS NIH HHS UL1 TR001881Wellcome Trust
6 · The paper itself

Abstract

Highly heritable, polygenic, and easily measured, adult height has long been the model trait in human genetics

Identifiers

PMID42396316
PMCPMC13321104

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.