Evidence map›Paper›PMID 42396307›Full record

ArticlemedRxiv : the preprint server for health sciences2026

Dengue and chikungunya virus transmission in Kinshasa, Democratic Republic of the Congo.

Rachel Sendor, Jessie Edwards, Kristin Banek, Melchior Mwandagalirwa Kashamuka, Justin Lessler, Daniel O Espinoza, Izabella N Castillo, Fabien Vulu, Nono Mvuama, Joseph A Bala and 12 more

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Rachel SendorUniversity of North Carolina at Chapel Hill, Gillings School of Global Public Health, Chapel Hill, North Carolina, United States of America.ORCID 0000-0001-7259-1514
Jessie EdwardsUniversity of North Carolina at Chapel Hill, Gillings School of Global Public Health, Chapel Hill, North Carolina, United States of America.ORCID 0000-0003-0770-1179
Kristin BanekTulane University, Celia Scott Weatherhead School of Public Health and Tropical Medicine, New Orleans, LA, United States of America.ORCID 0000-0001-9219-2852
Melchior Mwandagalirwa KashamukaUniversity of Kinshasa, Ecole de Santé Publique, Faculté de Médecine, Kinshasa, Democratic Republic of the Congo.
Justin LesslerUniversity of North Carolina at Chapel Hill, Gillings School of Global Public Health, Chapel Hill, North Carolina, United States of America.ORCID 0000-0002-9741-8109
Daniel O EspinozaEmory University, Division of Infectious Diseases, Atlanta, Georgia, United States of America.
Izabella N CastilloUniversity of North Carolina at Chapel Hill, Department of Microbiology and Immunology, Chapel Hill, North Carolina, United States of America.
Fabien VuluUniversity of Kinshasa, Department of Tropical Medicine, Faculté de Médecine, Kinshasa, Democratic Republic of the Congo.
Nono MvuamaUniversity of Kinshasa, Ecole de Santé Publique, Faculté de Médecine, Kinshasa, Democratic Republic of the Congo.
Joseph A BalaUniversity of Kinshasa, Ecole de Santé Publique, Faculté de Médecine, Kinshasa, Democratic Republic of the Congo.
Marthe NkalaniUniversity of Kinshasa, Ecole de Santé Publique, Faculté de Médecine, Kinshasa, Democratic Republic of the Congo.
Georges KihumaUniversity of Kinshasa, Ecole de Santé Publique, Faculté de Médecine, Kinshasa, Democratic Republic of the Congo.
Joseph AtibuUniversity of Kinshasa, Ecole de Santé Publique, Faculté de Médecine, Kinshasa, Democratic Republic of the Congo.
Tommy NsekaUniversity of Kinshasa, Ecole de Santé Publique, Faculté de Médecine, Kinshasa, Democratic Republic of the Congo.
Kyaw L ThwaiUniversity of North Carolina at Chapel Hill, Institute for Global Health and Infectious Diseases, Chapel Hill, North Carolina, United States of America.
Lakshmanane PremkumarUniversity of North Carolina at Chapel Hill, Department of Microbiology and Immunology, Chapel Hill, North Carolina, United States of America.
Rhoel R DinglasanUniversity of Florida, College of Veterinary Medicine, Gainesville, Florida, United States of America.
Michael EmchUniversity of North Carolina at Chapel Hill, Gillings School of Global Public Health, Chapel Hill, North Carolina, United States of America.
Jonathan J JulianoUniversity of North Carolina at Chapel Hill, Gillings School of Global Public Health, Chapel Hill, North Carolina, United States of America.
Matthew H CollinsEmory University, Division of Infectious Diseases, Atlanta, Georgia, United States of America.
Antoinette TshefuUniversity of Kinshasa, Ecole de Santé Publique, Faculté de Médecine, Kinshasa, Democratic Republic of the Congo.
Jonathan B ParrUniversity of North Carolina at Chapel Hill, Institute for Global Health and Infectious Diseases, Chapel Hill, North Carolina, United States of America.ORCID 0000-0002-4465-9830

Funding

Training in Infectious Disease Epidemiology (TIDE)T32AI070114 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Brian W Pence · 2007 to 2026
$4.0M
RDT-undetectable Malaria in the DR Congo: Epidemiology and Development of AlternativesR01AI132547 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DINGLASAN, RHOEL DAVID RAMOS, JULIANO, JONATHAN J · 2018 to 2022
$3.6M
A longitudinal epidemiological and epidemiological study of malaria and its vectors in the Kinshasa provinceR01AI129812 · NIAID · KINSHASA SCHOOL OF PUBLIC HEALTH · PI TSHEFU, ANTOINETTE KITOTO · 2017 to 2021
$674k
NIAID NIH HHS R01 AI129812NIAID NIH HHS R01 AI132547NIAID NIH HHS T32 AI070114
6 · The paper itself

Abstract

Dengue (DENV) and chikungunya (CHIKV) are understudied in the Democratic Republic of the Congo (DRC) and across Africa despite evidence of transmission. We measured DENV and CHIKV IgG seroprevalences in Kinshasa Province, DRC, by antigen-capture ELISA, using dried blood spots from 2021. Force of infection (FOI) was estimated from age-stratified seroprevalences using Bayesian catalytic modeling. Among 1,250 participants, DENV IgG seroprevalence was 38.1% (95% CI: 34.5%-41.8%), increasing with age, and highest within peri-urban Kimpoko sites (54.9%). CHIKV IgG seroprevalence was 24.2% (95% CI: 21.1%-27.6%), increasing with age and comparable between peri-urban Kimpoko and rural Bu, with few seropositives in the city-center. DENV-CHIKV IgG co-occurrence was detected in 12.8% of participants. Time-varying FOI models provided best fit to age-stratified seroprevalences, with spatial variation detected. Sustained DENV and CHIKV circulation across Kinshasa highlights an under-appreciated transmission risk and underscores the need for strengthened arboviral surveillance in the DRC and surrounding region.

Indexed as

AedesarbovirusesChikungunya virusDemocratic Republic of the CongoDengue virusDRCforce of infectionperi-urban transmissionseroprevalence

Identifiers

PMID42396307
PMCPMC13320923

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.