ArticleFrontiers in medicine2026
Respiratory safety and resource utilization in ERCP: a comparative study of high-flow nasal oxygen, conventional mask, and general anesthesia in high-risk populations.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Endoscopic retrograde cholangiopancreatography (ERCP) poses significant respiratory challenges due to shared airways, prone positioning and deep sedation requirements. High-flow nasal oxygen (HFNO) has emerged as a potential non-invasive oxygenation strategy. This study compared the clinical efficacy and volumetric oxygen consumption of HFNO with conventional simple mask (SM) oxygenation and general anesthesia (GA) in ERCP procedures. Methods: This retrospective cohort study included 194 adult patients (SM: Results: Desaturation occurred in 59.7% of SM patients versus 0% in both HFNO and GA groups ( Conclusion: HFNO provided a high level of respiratory stability, matching the observed 0% desaturation rate of the GA group, even in high-risk populations. While the anesthetic paradigms differ fundamentally, our findings suggest that HFNO can achieve a safety profile that approximates the clinical outcomes of general anesthesia regarding oxygenation maintenance.
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