Evidence map›Paper›PMID 42396010›Full record

ArticleACS omega2026

CMA-Nano: A DNA Methylation Detection Method for Nanopore Sequencing Data Based on a Cross-Modal Attention Mechanism.

Hua Shi, Chenglin Yin, Jianbo Qiao, Wenjia Gao, Leyi Wei

Abstract read
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hua ShiSchool of Optoelectronic and Communication Engineering, Xiamen University of Technology, Xiamen 361024, China.ORCID https://orcid.org/0000-0001-8812-5737
Chenglin YinSchool of Software, Shandong University, Jinan 250101, China.
Jianbo QiaoSchool of Software, Shandong University, Jinan 250101, China.
Wenjia GaoSchool of Software, Shandong University, Jinan 250101, China.
Leyi WeiFaculty of Applied Sciences, Macao Polytechnic University, Macao 999078, China.ORCID https://orcid.org/0000-0003-1444-190X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA methylation, particularly 5-methylcytosine (5mC), plays a pivotal role in gene regulation, development, and disease progression. Nanopore sequencing enables direct methylation detection without chemical treatment, but inherent signal noise and complex multimodal data pose analytical challenges. We present CMA-Nano, a deep learning framework that employs a cross-modal attention mechanism to integrate DNA sequences, nanopore signal statistics, and raw current signals, achieving effective fusion of multimodal features and capturing complex interdependencies. To further enhance feature representation and generalization, CMA-Nano leverages a masked base prediction pretraining strategy. Comprehensive evaluation on

Identifiers

PMID42396010
PMCPMC13325365

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.