Evidence map›Paper›PMID 42395766›Full record

ReviewRSC advances2026

Recent advances in thiazole-based derivatives targeting diverse anti-inflammatory pathways.

Dina H Dawood, Sami A Al-Hussain, Thoraya A Farghaly, Amani M R Alsaedi, Magdi E A Zaki

Abstract readReview
In one paragraph

Review in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dina H DawoodChemistry of Natural and Microbial Products Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre Dokki Giza 12622 Egypt.
Sami A Al-HussainDepartment of Chemistry, Faculty of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU) Riyadh 11623 Saudi Arabia MEZAKI@imamu.edu.sa.
Thoraya A FarghalyDepartment of Chemistry, Faculty of Science, Umm Al-Qura University Makkah Saudi Arabia tamohamed@uqu.edu.sa thoraya-f@hotmail.com.ORCID https://orcid.org/0000-0002-9620-8548
Amani M R AlsaediDepartment of Chemistry, Collage of Science, Taif University P. O. Box 11099 Taif 21944 Saudi Arabia.
Magdi E A ZakiDepartment of Chemistry, Faculty of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU) Riyadh 11623 Saudi Arabia MEZAKI@imamu.edu.sa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Various acute and chronic disorders, such as cancer, neurological diseases, cardiovascular disorders, and arthritis, are linked to inflammation. However, the long-term utilization of the available anti-inflammatory medications is frequently restricted by side effects and inadequate selectivity, emphasizing the need for safer and more effective therapeutic agents. A thiazole scaffold emerged as a unique framework in medicinal chemistry owing to its prominent biological effectiveness and favorable pharmacokinetic characteristics. Recently, substantial interest has been gained by various thiazole-based derivatives as potential anti-inflammatory drugs. The thiazole-containing derivatives have exerted prominent anti-inflammatory effects

Identifiers

PMID42395766
PMCPMC13325021

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.