Evidence map›Paper›PMID 42395708›Full record

ArticleRSC advances2026

Hybrid amine-derived compounds as cytotoxic anticancer leads: design, synthesis, and biological evaluation.

Reem Odeh, Areej M Jaber, Mazen Al-Sulaibi, Hamdi Nsairat, Mutasem O Taha

Abstract read
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Reem OdehPharmacological and Diagnostic Research Center, Faculty of Pharmacy, Al-Ahliyya Amman University Amman 19328 Jordan a.jaber@ammanu.edu.jo.
Areej M JaberPharmacological and Diagnostic Research Center, Faculty of Pharmacy, Al-Ahliyya Amman University Amman 19328 Jordan a.jaber@ammanu.edu.jo.ORCID https://orcid.org/0000-0002-2991-1858
Mazen Al-SulaibiPharmacological and Diagnostic Research Center, Faculty of Pharmacy, Al-Ahliyya Amman University Amman 19328 Jordan a.jaber@ammanu.edu.jo.
Hamdi NsairatPharmacological and Diagnostic Research Center, Faculty of Pharmacy, Al-Ahliyya Amman University Amman 19328 Jordan a.jaber@ammanu.edu.jo.ORCID https://orcid.org/0000-0001-5916-5879
Mutasem O TahaDrug Discovery Unit, Faculty of Pharmacy, The University of Jordan Amman Jordan.ORCID https://orcid.org/0000-0002-4453-072X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aurora kinases are key regulators of cell division and promising therapeutic targets in cancer treatment, particularly Aurora-A kinase, which is overexpressed in many tumors and associated with malignant progression. In this study, a series of novel amine-based hybrid molecules were designed and synthesized

Identifiers

PMID42395708
PMCPMC13326681

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.