Evidence map›Paper›PMID 42395669›Full record

ArticleWorld journal of nephrology2026

Multicentre comparative study of neural epidermal growth factor-like 1 protein

Subrahmanian Sathiavageesan, Abirami Krishnan, Krishnaswamy Sampathkumar, Ranjanee Muthu

Abstract read
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Article in World journal of nephrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Subrahmanian SathiavageesanDepartment of Nephrology, Sundaram Hospital, Tiruchirappalli 620017, Tamil Nādu, India. spssubrahmanian@yahoo.co.in.
Abirami KrishnanDepartment of Nephrology, Kauvery Hospital, Salem 636201, Tamil Nādu, India.
Krishnaswamy SampathkumarDepartment of Nephrology, Meenakshi Mission Hospital, Madurai 625107, Tamil Nādu, India.
Ranjanee MuthuDepartment of Nephrology, Apollo Hospitals, Chennai 600006, Tamil Nādu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe understanding of membranous nephropathy (MN) has significantly evolved with the discovery of novel antigenic targets. M-type phospholipase A2 receptor-associated MN (PLA2R-MN) is the most common antigenic variant, followed by neural epidermal growth factor-like 1 protein-associated MN (NELL1-MN). Few studies have directly compared the outcomes of these two variants.

aimTo compare the outcomes of NELL1-MN with PLA2R-MN.

methodsIn this retrospective cohort study, we compared the outcomes of NELL1-MN and PLA2R-MN using time-to-event analysis. Rate of remission - complete or partial - was the primary outcome of interest.

resultsThe 17 patients diagnosed with NELL1-MN during the study period were compared with 24 patients with PLA2R-MN diagnosed during the same month. Antecedent exposure to traditional indigenous medicines was more common in NELL1-MN than PLA2R-MN (70.6%

conclusionNELL1-MN has a favourable prognosis compared to PLA2R-MN. Antigen-specific outcomes research could inform prognosis and guide treatment strategies in MN.

Indexed as

GlomerulonephritisMembranous nephroparhyM-type phospolipase A2 receptorNephrotic syndromeNeural epidermal growth factor-like 1

Identifiers

PMID42395669
PMCPMC13324629

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