Evidence map›Paper›PMID 42395657›Full record

ArticleWorld journal of nephrology2026

Predictors of one-year mortality in hemodialysis patients with end-stage renal disease at a Kenyan county hospital.

Felix Pius Omullo, Thomas Kimanzi Kitheghe, Maureen Mueni Mark, Allan Kariuki Ng'ang'a, Magdalene Wanjiru Parsimei, Wambugu Charles Kanyi, Ooko Anyang'o Emma, Ismail Abdi Sheikh, Joshua Macharia Gitumu, Abel Mwangi Gakuya and 3 more

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Article in World journal of nephrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Felix Pius OmulloDepartment of Internal Medicine and Critical Care, Murang'a County Referral Hospital, Murang'a 69-10200, Central, Kenya. piuskirasia@gmail.com.
Thomas Kimanzi KithegheDepartment of Internal Medicine and Critical Care, Murang'a County Referral Hospital, Murang'a 69-10200, Central, Kenya.
Maureen Mueni MarkDepartment of Internal Medicine and Critical Care, Murang'a County Referral Hospital, Murang'a 69-10200, Central, Kenya.
Allan Kariuki Ng'ang'aDepartment of Internal Medicine and Critical Care, Murang'a County Referral Hospital, Murang'a 69-10200, Central, Kenya.
Magdalene Wanjiru ParsimeiDepartment of Internal Medicine and Critical Care, Murang'a County Referral Hospital, Murang'a 69-10200, Central, Kenya.
Wambugu Charles KanyiDepartment of Internal Medicine and Critical Care, Murang'a County Referral Hospital, Murang'a 69-10200, Central, Kenya.
Ooko Anyang'o EmmaDepartment of Internal Medicine and Critical Care, Murang'a County Referral Hospital, Murang'a 69-10200, Central, Kenya.
Ismail Abdi SheikhDepartment of Internal Medicine and Critical Care, Murang'a County Referral Hospital, Murang'a 69-10200, Central, Kenya.
Joshua Macharia GitumuDepartment of Internal Medicine and Critical Care, Murang'a County Referral Hospital, Murang'a 69-10200, Central, Kenya.
Abel Mwangi GakuyaDepartment of Internal Medicine and Critical Care, Murang'a County Referral Hospital, Murang'a 69-10200, Central, Kenya.
Glory Kawira GitongaDepartment of Internal Medicine and Critical Care, Murang'a County Referral Hospital, Murang'a 69-10200, Central, Kenya.
John Alex Ndung'uDepartment of Internal Medicine and Critical Care, Murang'a County Referral Hospital, Murang'a 69-10200, Central, Kenya.
Elisheba Moraa NyaroDepartment of Internal Medicine and Critical Care, Murang'a County Referral Hospital, Murang'a 69-10200, Central, Kenya.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn Kenya, end-stage renal disease (ESRD) poses a significant public health burden. While hemodialysis is primarily delivered through county hospitals, comprehensive outcome data from these routine clinical settings remain scarce.

aimTo evaluate one-year clinical outcomes and identify independent predictors of mortality among ESRD patients undergoing hemodialysis at a Kenyan county hospital.

methodsWe conducted a retrospective cohort study of all patients who initiated hemodialysis for ESRD at Murang'a County Referral Hospital between January 2024 and January 2025. Data on demographics, clinical characteristics, comorbidities, and treatment parameters were extracted from electronic medical records and dialysis unit logs. Cox proportional hazards regression was used to identify factors associated with one-year mortality.

resultsAmong 79 patients analyzed [median age 62.0 years, interquartile range (IQR) 48.0-74.0; 65.8% male], the cumulative all-cause mortality rate during the study period was 34.2% (27/79). The cohort demonstrated a heavy reliance on central venous catheters (CVCs) (89.9%, 71/79) rather than arteriovenous fistulas (10.1%, 8/79). Non-survivors were significantly older (median 73.0 years

conclusionMortality among hemodialysis patients in this Kenyan cohort is high, with older age and CVC use strongly associated with poorer survival. The near-universal reliance on CVCs highlights systemic challenges in pre-dialysis care, underscoring the urgent need for robust vascular access programs and early intervention strategies to improve patient outcomes.

Indexed as

Central venous catheterEnd-stage renal diseaseHemodialysisKenyaPredictorsVascular access

Identifiers

PMID42395657
PMCPMC13324625

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.