Evidence map›Paper›PMID 42395621›Full record

ArticleFrontiers in nutrition2026

Chemical profiling and

Abderrazek Ferhat, Mohammed Messaoudi, Khalil Guelifet, Ilham Ben Amor, Wafa Zahnit, Khadra Afaf Bendrihem, Azzeddine Zeraib, Hamza Ouakouak, Mokhtar Benmohamed, Mohamed Amine Ferhat and 6 more

Abstract read
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In one paragraph

Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Abderrazek FerhatLaboratory of Research in Science and Environment: Bioresources, Geochemistry-Physics, Legislation and Socio-Economic Development, Faculty of Sciences and Technology, University of Tamanghasset, Tamanrasset, Algeria.
Mohammed MessaoudiLaboratory of Research on Bio-Active Products and Valorization of Biomass, Ecole Normale Supérieure, Algiers, Algeria.
Khalil GuelifetLaboratory of Research on Bio-Active Products and Valorization of Biomass, Ecole Normale Supérieure, Algiers, Algeria.
Ilham Ben AmorDepartment of Process Engineering and Petrochemical, Faculty of Technology, University of El Oued, El Oued, Algeria.
Wafa ZahnitDepartment of Chemistry, Faculty of Sciences, University of Ferhat ABBAS Setif 1, Setif, Algeria.
Khadra Afaf BendrihemBiotechnology, Water, Environment and Health Laboratory, Faculty of Natural and Life Sciences, University of Abbes Laghrour, Khenchela, Algeria.
Azzeddine ZeraibBiotechnology, Water, Environment and Health Laboratory, Faculty of Natural and Life Sciences, University of Abbes Laghrour, Khenchela, Algeria.
Hamza OuakouakDepartment of Process Engineering and Petrochemical, Faculty of Technology, University of El Oued, El Oued, Algeria.
Mokhtar BenmohamedDepartment of Physics, Saida Higher Teacher Training School, Saida, Algeria.
Mohamed Amine FerhatLaboratory of Research on Bio-Active Products and Valorization of Biomass, Ecole Normale Supérieure, Algiers, Algeria.
Imane LarkemFSNV, Département Sciences Agronomiques, Université Ferhat Abbas de Sétif, Sétif, Algeria.
Huda AlsaeediDepartment of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.
Aftab Aslam Parwaz KhanCenter of Excellence for Advanced Materials Research, King Abdulaziz University, Jeddah, Saudi Arabia.
Mikhael BechelanyInstitut Européen des Membranes, IEM, UMR 5635, Univ Montpellier, ENSCM, CNRS, Montpellier, France.
Furong TianNanolab Research Centre, Physical to Life Sciences Research Hub, Technological University Dublin, Dublin, Ireland.
Ahmed BarhoumSchool of Chemical and BioPharmaceutical Sciences, Technological University Dublin, Dublin, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: This study aimed to investigate the phytochemical composition and multifunctional therapeutic potential of a hydroethanolic extract of Methods: Total polyphenol and flavonoid contents were determined using spectrophotometric methods. The phytochemical profile was characterized by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS). Antioxidant activity was assessed using DPPH and galvinoxyl radical scavenging assays. Antimicrobial activity was evaluated against bacterial and fungal strains using inhibition zone measurements. Enzyme inhibitory activities against α-amylase, acetylcholinesterase, and butyrylcholinesterase were investigated Results: The extract contained high levels of total polyphenols (41.9 mg gallic acid equivalent/g extract) and flavonoids (17.1 mg rutin equivalent/g extract). LC-MS/MS analysis identified several bioactive compounds, including caffeic acid, gallocatechin gallate, and apigenin-7-O-glucoside. The extract exhibited moderate antioxidant activity, with IC50 values of 324.4 μg/mL and 22.7 μg/mL for DPPH and galvinoxyl assays, respectively. Strong antimicrobial effects were observed against Discussion: The findings demonstrate that

Indexed as

anti-Alzheimerantibacterialantidiabeticanti-inflammatoryantioxidantMatricaria chamomilla L.medicinal plants

Identifiers

PMID42395621
PMCPMC13323515

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.