ArticlebioRxiv : the preprint server for biology2026
Spatial Transcriptomic Profiling Reveals Microenvironment-Dependent Immune Signatures in a Lyme Arthritis model.
Kaitlyn Gura, Mollie Hostetter, Veena Potluri, Michael Hill, Sarah Johnson, Yuelin Zhong, Eleanor Astley, Tanja Petnicki-Ocwieja, Suba Nookala, Catherine Brissette and 1 more
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
11 authors.
Kaitlyn GuraDepartment of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND, USA.ORCID 0009-0003-4456-4238 Mollie HostetterDepartment of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND, USA.
Veena PotluriDepartment of Pathology, ALTRU Health System, Grand Forks, ND, USA.
Michael HillDepartment of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND, USA.
Sarah JohnsonDepartment of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND, USA.
Yuelin ZhongDepartment of Molecular Biology and Microbiology, Tufts University, Boston, Massachusetts, USA.
Eleanor AstleyDepartment of Molecular Biology and Microbiology, Tufts University, Boston, Massachusetts, USA.
Tanja Petnicki-OcwiejaDepartment of Molecular Biology and Microbiology, Tufts University, Boston, Massachusetts, USA.ORCID 0000-0002-4048-5300 Suba NookalaDepartment of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND, USA.ORCID 0000-0002-4632-265X Catherine BrissetteDepartment of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND, USA.ORCID 0000-0003-0792-1403 Archana DhasarathyDepartment of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND, USA.ORCID 0000-0002-8251-6136 Funding
The role of class IIa Hdac in regulating cell fate choice in early cortical development.P20GM104360 · NIGMS · UNIVERSITY OF NORTH DAKOTA · PI ROCHE, BENJAMIN · 2013 to 2023
$21.1MTracking and Evaluation CoreU54GM128729 · NIGMS · UNIVERSITY OF NORTH DAKOTA · PI BASSON, MARC D. · 2018 to 2022
$20.3MYersina perstis interactions with macrophagesP20GM113123 · NIGMS · UNIVERSITY OF NORTH DAKOTA · PI COMBS, COLIN K · 2016 to 2025
$19.9MNIGMS NIH HHS P20 GM104360NIGMS NIH HHS P20 GM113123NIGMS NIH HHS U54 GM128729
6 · The paper itselfAbstract
Lyme arthritis, a manifestation of Lyme disease, is triggered by the spirochetal bacterium
Indexed as
arthritisLyme diseasemousespatial transcriptomics
Identifiers
PMID42395505
PMCPMC13320799
What OpenQuestion holds
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