Evidence map›Paper›PMID 42395491›Full record

ArticlebioRxiv : the preprint server for biology2026

Homeostatic Plasticity Enables Stable yet Tunable Neuronal Assemblies.

Michelle C Miller, Christoph Miehl, Brent Doiron

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michelle C MillerCommittee on Computational Neuroscience. Grossman Center for Quantitative Biology and Human Behavior University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-1638-9570
Christoph MiehlDepartment of Neurobiology Grossman Center for Quantitative Biology and Human Behavior University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0001-9094-2760
Brent DoironDepartments of Neurobiology and Statistics Grossman Center for Quantitative Biology and Human Behavior University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-6916-5511

Funding

Validating Theoretical Models with Neurophysiology and OptogeneticsU19NS107613 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI JI, NA · 2018 to 2022
$16.7M
Cortical assembly formation through excitatory/inhibitory circuit plasticityR01NS133598 · NINDS · UNIVERSITY OF CHICAGO · PI Brent D. Doiron, Anne-Marie Michelle Oswald · 2026 to 2026
$612k
NINDS NIH HHS R01 NS133598NINDS NIH HHS U19 NS107613
6 · The paper itself

Abstract

Strongly interconnected neuronal populations, called assemblies, dynamically form through synaptic plasticity mechanisms and are thought to be a substrate for memories in the brain. Many assembly formation models use Hebbian excitatory-to-excitatory plasticity, where coordinated activity strengthens recurrent structure. However, these models typically yield binary assembly outcomes: networks with either weak (no assembly) or maximally strong (assembly) connectivity. We consider networks with a combination of Hebbian excitatory-to-excitatory plasticity and inhibitory-to-excitatory synapses with plasticity that homeostatically stabilizes excitatory neuron firing at a target value. When we set excitatory-to-excitatory plasticity to be

Identifiers

PMID42395491
PMCPMC13320947

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.