Evidence map›Paper›PMID 42395468›Full record

ArticlebioRxiv : the preprint server for biology2026

Assessing

Yaëlle Wormser, Emilie Yab, Adrià Sogues, Francesca Gubellini, Estelle Capton, Estelle Lecat, Mathilde Ben Assaya, Alexandra Aubry, Ariel Mechaly, Pedro M Alzari and 3 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yaëlle WormserInstitut Pasteur, Université Paris Cité, CNRS UMR 3528, Bacterial Cell Cycle Mechanisms Unit, F-75015 Paris, France.
Emilie YabInstitut Pasteur, Université Paris Cité, CNRS UMR 3528, Structural Microbiology Unit, F-75015 Paris, France.
Adrià SoguesInstitut Pasteur, Université Paris Cité, CNRS UMR 3528, Bacterial Cell Cycle Mechanisms Unit, F-75015 Paris, France.
Francesca GubelliniInstitut Pasteur, Université Paris Cité, CNRS UMR 3528, Structural Microbiology Unit, F-75015 Paris, France.
Estelle CaptonSorbonne Université, CNRS, INSERM, Centre d'Immunologie et des Maladies Infectieuses, CIMI, Paris, France.
Estelle LecatInstitut Pasteur, Université Paris Cité, CNRS UMR 3528, Structural Microbiology Unit, F-75015 Paris, France.
Mathilde Ben AssayaInstitut Pasteur, Université Paris Cité, CNRS UMR 3528, Bacterial Cell Cycle Mechanisms Unit, F-75015 Paris, France.
Alexandra AubrySorbonne Université, CNRS, INSERM, Centre d'Immunologie et des Maladies Infectieuses, CIMI, Paris, France.
Ariel MechalyInstitut Pasteur, Université Paris Cité, Plateforme de Cristallographie, C2RT, CNRS UMR 3528, 75015 Paris, France.
Pedro M AlzariInstitut Pasteur, Université Paris Cité, CNRS UMR 3528, Structural Microbiology Unit, F-75015 Paris, France.
Anne Marie WehenkelInstitut Pasteur, Université Paris Cité, CNRS UMR 3528, Bacterial Cell Cycle Mechanisms Unit, F-75015 Paris, France.
Antoine GedeonInstitut Pasteur, Université Paris Cité, CNRS UMR 3528, Structural Microbiology Unit, F-75015 Paris, France.ORCID 0000-0003-0301-8786
Stéphanie PetrellaInstitut Pasteur, Université Paris Cité, CNRS UMR 3528, Bacterial Cell Cycle Mechanisms Unit, F-75015 Paris, France.ORCID 0000-0001-6641-5901

Funding

ChimeraX -- Next Generation Visualization and Analysis Software for Multiscale ModelingR01GM129325 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FERRIN, THOMAS E · 2018 to 2025
$5.2M
NIGMS NIH HHS R01 GM129325
6 · The paper itself

Abstract

DNA gyrase is an essential bacterial enzyme and a clinically validated target for the treatment of tuberculosis. However, the discovery of new inhibitors remains limited by the many challenges regarding the manipulation on pathogenic mycobacteria. This study validates

Identifiers

PMID42395468
PMCPMC13321055

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.