Evidence map›Paper›PMID 42395419›Full record

ArticlebioRxiv : the preprint server for biology2026

Amphotericin B Resistance in

Nina T Grossman, Arturo Casadevall

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Nina T GrossmanDepartment of Molecular Microbiology and Immunology, Johns Hopkins School of Public Health.
Arturo CasadevallDepartment of Molecular Microbiology and Immunology, Johns Hopkins School of Public Health.ORCID 0000-0002-9402-9167

Funding

Pharmacology/Mycology CoreU19AI189183 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Arturo Casadevall, David S Perlin · 2025 to 2026
$21.2M
Training: Molecular & Cellular Bases of Infectious DiseasesT32AI007417 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Arturo Casadevall · 1994 to 2026
$11.9M
Synergy of Host Defense Mechanisms in the LungR01HL059842 · NHLBI · YESHIVA UNIVERSITY · PI CASADEVALL, ARTURO · 1997 to 2023
$7.4M
Biology of Fungal MelaninR01AI052733 · NIAID · YESHIVA UNIVERSITY · PI CASADEVALL, ARTURO · 2003 to 2019
$6.6M
Conjugate vaccines for prevention and treatment of cryptococcosis - COVID-19 Revision SupplementR01AI152078 · NIAID · JOHNS HOPKINS UNIVERSITY · PI CASADEVALL, ARTURO · 2020 to 2024
$5.1M
NHLBI NIH HHS R01 HL059842NIAID NIH HHS R01 AI052733NIAID NIH HHS R01 AI152078NIAID NIH HHS T32 AI007417NIAID NIH HHS U19 AI189183
6 · The paper itself

Abstract

Introduction: Objectives: We aimed to investigate the mechanism of resistance to AMB of Methods: The AMB susceptibility of Results: AMB was 16-fold more effective in inhibiting the growth of Conclusion: We report a different mechanism for AMB resistance based on the existence of a substance residing in the

Indexed as

amphotericin bLomentospora prolificansresistance

Identifiers

PMID42395419
PMCPMC13320748

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.