Evidence map›Paper›PMID 42395248›Full record

ArticleCureus2026

Potential of Thiocolchicoside as an Antimicrobial Repurposing Agent: An In Vitro Study.

Akash V Devi, Chitra Khanwelkar

Abstract read
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Akash V DeviPharmacology, Krishna Institute of Medical Sciences, Krishna Vishwa Vidyapeeth (Deemed to be University), Karad, IND.
Chitra KhanwelkarPharmacology, Krishna Institute of Medical Sciences, Krishna Vishwa Vidyapeeth (Deemed to be University), Karad, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial resistance (AMR) is a global health emergency that poses a hazard to the effective management of infectious diseases. Drug repurposing provides a cost-effective and expeditious solution by identifying new applications for existing pharmaceuticals. A semi-synthetic derivative of colchicoside, thiocolchicoside (THC), has been recently investigated for its potential anticancer and antimicrobial properties. It is prescribed as a muscle relaxant. THC was tested against a variety of gram-positive and gram-negative bacteria, as well as fungal isolates, at concentrations ranging from 4000 to 62.5 µg/mL. Standard antibacterial and antifungal controls were provided by gentamicin (GN) and fluconazole (FZ). Turbidity and absorbance-based assays at 600 nm were employed to ascertain the minimum inhibitory concentrations (MICs). THC demonstrated MICs of 125 µg/mL against

Indexed as

drug repurposinggram-negative bacteriagram-positive bacteriaminimum inhibitory concentration (mic)thiocolchicoside

Identifiers

PMID42395248
PMCPMC13326860

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.