Evidence map›Paper›PMID 42395182›Full record

ReviewFrontiers in endocrinology2026

The influence of hormonal changes during pregnancy on bone metabolism - a mini review.

Anna Brona, Barbara Stachowska, Marek Bolanowski, Jowita Halupczok-Żyła

Abstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anna BronaDepartment and Clinic of Endocrinology and Internal Medicine, Wrocław Medical University, Wrocław, Poland.
Barbara StachowskaDepartment and Clinic of Endocrinology and Internal Medicine, Wrocław Medical University, Wrocław, Poland.
Marek BolanowskiDepartment and Clinic of Endocrinology and Internal Medicine, Wrocław Medical University, Wrocław, Poland.
Jowita Halupczok-ŻyłaDepartment of Clinical and Experimental Pathology, Wrocław Medical University, Wrocław, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During pregnancy, the maternal endocrine system undergoes a profound hormonal transformation to support fetal development. Although these changes are essential, they significantly affect maternal bone metabolism and may result in a rare but serious condition known as Pregnancy and Lactation-Associated Osteoporosis (PLO). Despite the change in maternal hormone production, there is a new player - a placenta, which makes a substantial contribution to the bone remodeling process. Most publications address the influence of parathyroid hormone, prolactin, and growth hormone. However, data on the interactions between other hormones and skeletal system cells remain limited. Our mini-review focuses on the mechanism by which hormones influence the activity of osteoclasts and osteoblasts.

Indexed as

Bone and BonesBone RemodelingHormonesAnimalsFemaleHumansLactationOsteoblastsOsteoclastsOsteoporosisPregnancyHormonesACTHcortisolestrogengrowth hormoneIGF-1prolactinPTHrPTSH

Identifiers

PMID42395182
PMCPMC13322916

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.