Evidence map›Paper›PMID 42395127›Full record

ArticleAnnals of gastroenterological surgery2026

Risk Factors for Small-for-Size Syndrome Grade B/C After Simultaneous Splenectomy in Adult Living-Donor Liver Transplantation.

Kyohei Yugawa, Takeo Toshima, Shinji Itoh, Takashi Motomura, Shohei Yoshiya, Norifumi Iseda, Tomoharu Yoshizumi

Abstract read
In one paragraph

Article in Annals of gastroenterological surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kyohei YugawaDepartment of Surgery and Science, Graduate School of Medical Sciences Kyushu University Fukuoka Japan.ORCID https://orcid.org/0000-0002-3776-7913
Takeo ToshimaDepartment of Surgery and Science, Graduate School of Medical Sciences Kyushu University Fukuoka Japan.ORCID https://orcid.org/0000-0003-4019-8288
Shinji ItohDepartment of Surgery and Science, Graduate School of Medical Sciences Kyushu University Fukuoka Japan.ORCID https://orcid.org/0000-0003-0382-2520
Takashi MotomuraDepartment of Surgery and Science, Graduate School of Medical Sciences Kyushu University Fukuoka Japan.ORCID https://orcid.org/0009-0005-0417-9137
Shohei YoshiyaDepartment of Surgery and Science, Graduate School of Medical Sciences Kyushu University Fukuoka Japan.ORCID https://orcid.org/0000-0003-4642-5058
Norifumi IsedaDepartment of Surgery and Science, Graduate School of Medical Sciences Kyushu University Fukuoka Japan.
Tomoharu YoshizumiDepartment of Surgery and Science, Graduate School of Medical Sciences Kyushu University Fukuoka Japan.ORCID https://orcid.org/0000-0002-4497-1816

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Small-for-size syndrome (SFSS) after adult living-donor liver transplantation (LDLT) is a poor prognostic condition. Splenectomy (Spx) has recently been reported to help prevent SFSS and improve outcomes. This study aimed to identify risk factors for SFSS that occur despite Spx at the time of LDLT. Methods: This single-center retrospective study included 973 LDLT recipients from 2001 to 2024. Of these, 577 who underwent concomitant Spx were analyzed. SFSS grading followed the 2023 International Liver Transplantation Society consensus criteria. Prognostic factors associated with SFSS grade B/C, which required perioperative portal vein inflow control, were identified. Results: SFSS grade B/C occurred in 105 patients (18.2%) and was associated with significantly worse prognosis than grade 0/A (1-year survival: 93.9% vs. 81.9%, Conclusions: SFSS grade B/C still occurred in nearly one in five patients who underwent Spx for SFSS risk mitigation during LDLT. Patients with a high recipient NLR, MELD score, or donor age are at increased risk of SFSS despite Spx. Future strategies should emphasize careful donor selection and perioperative portal inflow modulation for high-risk cases.

Indexed as

living‐donor liver transplantationprognosissmall‐for‐size syndromesplenectomy

Identifiers

PMID42395127
PMCPMC13327040

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.