Evidence map›Paper›PMID 42395123›Full record

ArticleAnnals of gastroenterological surgery2026

Prognostic Significance of Portal Vein Tumor Thrombus in Pancreatic Ductal Adenocarcinoma Treated With Chemoradiotherapy.

Aoi Hayasaki, Motonori Nagata, Miki Usui, Hiroshi Imai, Yusuke Iizawa, Akihiro Tanemura, Yasuhiro Murata, Naohisa Kuriyama, Masashi Kishiwada, Shugo Mizuno

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Article in Annals of gastroenterological surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Aoi HayasakiDepartment of Hepato-Biliary-Pancreatic and Transplant Surgery Mie University Tsu Mie Japan.ORCID https://orcid.org/0000-0001-7189-357X
Motonori NagataDepartment of Radiology Mie University Tsu Mie Japan.
Miki UsuiPathology Division Mie University Hospital Tsu Mie Japan.
Hiroshi ImaiPathology Division Mie University Hospital Tsu Mie Japan.
Yusuke IizawaDepartment of Hepato-Biliary-Pancreatic and Transplant Surgery Mie University Tsu Mie Japan.
Akihiro TanemuraDepartment of Hepato-Biliary-Pancreatic and Transplant Surgery Mie University Tsu Mie Japan.
Yasuhiro MurataDepartment of Hepato-Biliary-Pancreatic and Transplant Surgery Mie University Tsu Mie Japan.ORCID https://orcid.org/0000-0001-5997-4342
Naohisa KuriyamaDepartment of Hepato-Biliary-Pancreatic and Transplant Surgery Mie University Tsu Mie Japan.ORCID https://orcid.org/0000-0002-9668-0500
Masashi KishiwadaDepartment of Hepato-Biliary-Pancreatic and Transplant Surgery Mie University Tsu Mie Japan.
Shugo MizunoDepartment of Hepato-Biliary-Pancreatic and Transplant Surgery Mie University Tsu Mie Japan.ORCID https://orcid.org/0000-0002-2253-544X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: To examine the significance of portal vein tumor thrombus (PVTT) as a prognostic factor for patients with pancreatic ductal adenocarcinoma (PDAC) treated with chemoradiotherapy (CRT) followed by surgery. Methods: The study retrospectively examined 313 patients with borderline resectable (BR) or locally advanced (LA) PDAC who underwent CRT between November 2008 and December 2023. PVTT was evaluated on computed tomography. Disease-specific survival (DSS) and overall survival (OS) were compared between patients with and without PVTT. Multivariate Cox analysis was conducted to examine the significance of PVTT as a prognostic factor. Subgroup analysis of patients who underwent resection ( Results: The PVTT and no PVTT groups comprised 25 (8.0%) and 288 (92.0%) patients, respectively. Median DSS (23.5 vs. 12.3 months) and OS (21.6 vs. 12.2 months) were significantly longer in the no PVTT group ( Conclusion: The presence of PVTT on computed tomography before CRT was an independent adverse prognostic factor in BR and LA PDAC patients enrolled in CRT.

Indexed as

pancreatic ductal adenocarcinomaportal vein invasionportal vein tumor thrombuspreoperative chemoradiotherapyrecurrence site

Identifiers

PMID42395123
PMCPMC13327083

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.