ArticleWorld journal of radiology2026
Evaluation of bicuspid aortic valve-associated aortopathic changes using third-generation dual-source computed tomography.
Article in World journal of radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundBicuspid aortic valve (BAV) affects 0.5%-2% of the population and is associated with progressive aortopathy leading to life-threatening complications. Aortic size index (ASI) adjusts aortic dimensions for body surface area (BSA), potentially improving risk stratification.
aimTo characterise BAV-associated aortopathic changes using third-generation dual-source computed tomography (CT) and to derive a cohort-specific ASI threshold associated with CT-defined ascending aortic dilatation in an Indian population.
methodsThis prospective cross-sectional study enrolled 100 BAV patients (age > 18 years) from July 2022 to November 2023. All patients underwent CT aortography using 192-slice third-generation dual-source CT scanner (Somatom Force, Siemens). Aortic measurements were obtained at multiple levels including annulus, sinus of Valsalva, ascending aorta, arch, and descending thoracic aorta. ASI was calculated as maximum ascending aortic diameter divided by BSA. Statistical analysis included receiver operating characteristic curve analysis and correlation coefficients.
resultsMean age was 48.95 ± 13.78 years, with 64% males. Ascending aortic dilatation was present in 87% of patients, with a mean diameter of 42.79 ± 8.69 mm. Mean ASI was 25.13 ± 5.71 mm/m
conclusionIn this single-centre cohort of Indian patients with BAVs, an ASI threshold of 23.8 mm/m
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