Evidence map›Paper›PMID 42395052›Full record

ArticleNpj gut and liver2026

Illustration of the gut-immune-liver axis in early-stage alcohol-related liver disease: role and non-invasive potentiation of biomarkers and peptidomic signatures.

Anjali Kumari, Mukesh Sriwastva, Michael Merchant, Christine Dolin, Gavin Arteel, Sabine Waigel, Maiying Kong, Melanie L Schwandt, Joris Verster, Ashwani K Singal and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Npj gut and liver, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Anjali KumariDivision of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Louisville, Louisville, KY USA.
Mukesh SriwastvaDepartment of Physiology, University of Louisville, Louisville, KY USA.
Michael MerchantDiv. of Nephrology and Hypertension, Department of Medicine, Louisville, KY USA.
Christine DolinDiv. of Nephrology and Hypertension, Department of Medicine, Louisville, KY USA.
Gavin ArteelDiv. of Nephrology and Hypertension, Department of Medicine, Louisville, KY USA.
Sabine WaigelGenomics Training and Education Center, University of Louisville, Louisville, KY USA.
Maiying KongDepartment of Bioinformatics and Biostatistics, University of Louisville, Louisville, KY USA.
Melanie L SchwandtNational Institute on Alcohol Abuse and Alcoholism, Bethesda, MD USA.
Joris VersterUtrecht University, Utrecht, Holland.
Ashwani K SingalDivision of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Louisville, Louisville, KY USA.
Venkatakrishna R JalaDepartment of Microbiology and Immunology, UofL, Louisville, KY USA.
Craig J McClainDivision of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Louisville, Louisville, KY USA.
Vatsalya VatsalyaDivision of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Louisville, Louisville, KY USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alcohol use disorder (AUD) can progress to alcohol-associated liver disease (ALD), yet early-stage ALD (eALD) remains poorly defined at the molecular level. We performed plasma proteomic and peptidomic analysis in 42 adults (AUD

Indexed as

BiochemistryBiomarkersDiseasesGastroenterologyImmunology

Identifiers

PMID42395052
PMCPMC13318631

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.