ArticleFrontiers in pharmacology2026
Phytochemical properties of
Article in Frontiers in pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Medicinal plants used in traditional systems of medicine are a valuable source of bioactive compounds with therapeutic potential against oxidative stress-related disorders, including male infertility. Purpose: This study aimed to evaluate the metabolites composition and dose-dependent effects of Methods: A total of 24 male mice were divided into four groups (n = 6) using a completely randomized design. The ethanol extract of Results: Analysis revealed the presence of flavonoids, phenolics, tannins, and alkaloids. The P3 treatment significantly improved sperm concentration by 155% compared to the control. However, the P2 treatment yielded the highest percentage of viable spermatozoa (85.78%), motility (39.28%), and normal morphology (84.67%), alongside enhanced seminiferous tubule structure and spermatogenic cell density. These effects are attributed to the ROS-scavenging activity of phytochemicals, which preserve cellular morphology and support spermatogenesis. Serum testosterone levels increased in a dose-dependent manner, correlating with Leydig cell proliferation. Notably, while the moderate dose (P2) resulted in optimal reproductive outcomes, the highest dose (P3) showed a decline in sperm quality and histological alterations. Conclusion:
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.